Controlled Oxygenated Rewarming Compensates for Cold Storage–induced Dysfunction in Kidney Grafts

C von Horn, H Zlatev, M Kaths, A Paul, T Minor - Transplantation, 2022 - journals.lww.com
Background. Normothermic machine perfusion (NMP) provides a promising strategy for
preservation and conditioning of marginal organ grafts. However, at present, high logistic …

[HTML][HTML] Improved approach for normothermic machine perfusion of cold stored kidney grafts

C von Horn, T Minor - American Journal of Translational Research, 2018 - ncbi.nlm.nih.gov
Normothermic machine perfusion can decrease reperfusion injury in renal transplantation.
Clinical procurement logistics include retrieval and initial transport of the graft using static …

Prolonged controlled oxygenated rewarming improves immediate tubular function and energetic recovery of porcine kidneys during normothermic machine perfusion

B Ogurlu, CC Pamplona, IM Van Tricht… - …, 2023 - journals.lww.com
Background. Normothermic machine perfusion (NMP) is typically performed after a period of
hypothermic preservation, which exposes the kidney to an abrupt increase in temperature …

Controlled rewarming after hypothermia: adding a new principle to renal preservation

I Schopp, E Reissberg, B Lüer… - Clinical and …, 2015 - Wiley Online Library
Early graft dysfunction due to preservation/reperfusion injury still represents a notable issue
after kidney transplantation, affecting long term prognosis of graft viability. One trigger of …

One or 4 h of “in‐house” reconditioning by machine perfusion after cold storage improve reperfusion parameters in porcine kidneys

A Gallinat, P Efferz, A Paul, T Minor - Transplant International, 2014 - Wiley Online Library
In‐house machine perfusion after cold storage (hypothermic reconditioning) has been
proposed as convenient tool to improve kidney graft function. This study investigated the role …

Normothermic ex vivo perfusion of deceased donor kidneys and its clinical potential in kidney transplantation outcomes

M Unes, K Kurashima, Y Caliskan… - … Journal of Artificial …, 2023 - journals.sagepub.com
In recent years, normothermic machine perfusion (NMP) has emerged in conversation
surrounding organ preservation and transplantation techniques with the goal of improving …

Normothermic ex vivo kidney perfusion reduces warm ischemic injury of porcine kidney grafts retrieved after circulatory death

M Hamar, P Urbanellis, MJ Kaths, D Kollmann… - …, 2018 - journals.lww.com
Background Cold storage is poorly tolerated by kidney grafts retrieved after donation after
circulatory death. It has been determined that normothermic ex vivo kidney perfusion …

[HTML][HTML] Improved normothermic machine perfusion after short oxygenated hypothermic machine perfusion of ischemically injured porcine kidneys

S Lignell, S Lohmann, KM Rozenberg… - Transplantation …, 2021 - journals.lww.com
Background. In an era where global kidney shortage has pushed the field of transplantation
towards using more marginal donors, modified kidney preservation techniques are currently …

Oxygen consumption by warm ischemia-injured porcine kidneys in hypothermic static and machine preservation

J Kaminski, PO Delpech, S Kaaki-Hosni… - Journal of Surgical …, 2019 - Elsevier
Static cold storage (SCS) and hypothermic machine perfusion (HMP) are currently standard
methods for renal grafts clinical preservation. Both methods are predominantly implemented …

Advances in hypothermic and normothermic perfusion in kidney transplantation

TB Smith, ML Nicholson, SA Hosgood - Transplantology, 2021 - mdpi.com
Hypothermic and normothermic machine perfusion in kidney transplantation are purported
to exert a beneficial effect on post-transplant outcomes compared to the traditionally used …