[HTML][HTML] VEGFA isoforms as pro-angiogenic therapeutics for cerebrovascular diseases
AL White, GJ Bix - Biomolecules, 2023 - mdpi.com
Therapeutic angiogenesis has long been considered a viable treatment for vasculature
disruptions, including cerebral vasculature diseases. One widely-discussed treatment …
disruptions, including cerebral vasculature diseases. One widely-discussed treatment …
Delineating multiple functions of VEGF-A in the adult brain
Vascular endothelial growth factor-A (abbreviated throughout this review as VEGF) is mostly
known for its angiogenic activity, for its activity as a vascular permeability factor, and for its …
known for its angiogenic activity, for its activity as a vascular permeability factor, and for its …
Increased severity of cerebral ischemic injury in vascular endothelial growth factor-b–deficient mice
Y Sun, K Jin, JT Childs, L Xie, XO Mao… - Journal of Cerebral …, 2004 - journals.sagepub.com
Vascular endothelial growth factor-B (VegfB) is an angiogenic protein related to VegfA,
although it acts on a different set of tyrosine kinase receptors. Like VegfA, VegfB is …
although it acts on a different set of tyrosine kinase receptors. Like VegfA, VegfB is …
Vascular endothelial growth factor: a neurovascular target in neurological diseases
C Lange, E Storkebaum, CR De Almodóvar… - Nature Reviews …, 2016 - nature.com
Brain function critically relies on blood vessels to supply oxygen and nutrients, to establish a
barrier for neurotoxic substances, and to clear waste products. The archetypal vascular …
barrier for neurotoxic substances, and to clear waste products. The archetypal vascular …
VEGF in the nervous system
JM Rosenstein, JM Krum, C Ruhrberg - Organogenesis, 2010 - Taylor & Francis
Vascular endothelial growth factor (VEGF, VEGFA) is critical for blood vessel growth in the
developing and adult nervous system of vertebrates. Several recent studies demonstrate …
developing and adult nervous system of vertebrates. Several recent studies demonstrate …
New roles for VEGF in nervous tissue—beyond blood vessels
JM Rosenstein, JM Krum - Experimental neurology, 2004 - Elsevier
Vascular endothelial growth factor (VEGF) is a secreted dimeric polypeptide that until
recently has been believed to be a specific mitogen for endothelial cells subserving …
recently has been believed to be a specific mitogen for endothelial cells subserving …
Vascular endothelial growth factors (VEGFs) and stroke
DA Greenberg, K Jin - Cellular and molecular life sciences, 2013 - Springer
Vascular endothelial growth factors (VEGFs) have been shown to participate in
atherosclerosis, arteriogenesis, cerebral edema, neuroprotection, neurogenesis …
atherosclerosis, arteriogenesis, cerebral edema, neuroprotection, neurogenesis …
Diverse roles for VEGF-A in the nervous system
F Mackenzie, C Ruhrberg - Development, 2012 - journals.biologists.com
Vascular endothelial growth factor A (VEGF-A) is best known for its essential roles in blood
vessel growth. However, evidence has emerged that VEGF-A also promotes a wide range of …
vessel growth. However, evidence has emerged that VEGF-A also promotes a wide range of …
Critical questions for preclinical trials on safety and efficacy of vascular endothelial growth factor-based therapeutic angiogenesis for ischemic stroke
PS Manoonkitiwongsa - … Formerly Current Drug Targets-CNS & …, 2011 - ingentaconnect.com
Therapeutic angiogenesis is a novel treatment for ischemic stroke, and vascular endothelial
growth factor (VEGF) is a key angiogenic and neuroprotective pharmacological candidate …
growth factor (VEGF) is a key angiogenic and neuroprotective pharmacological candidate …
VEGF-B: a survival, or an angiogenic factor?
X Li, C Lee, Z Tang, F Zhang, P Arjunan… - Cell adhesion & …, 2009 - Taylor & Francis
Despite its early discovery and high sequence homology to the other VEGF family members,
the biological function of VEGF-B remained debatable for a long time, and VEGF-B has …
the biological function of VEGF-B remained debatable for a long time, and VEGF-B has …