Expression and function analysis of CRABP2 and FABP5, and their ratio in esophageal squamous cell carcinoma

M Li, C Li, P Lu, B Wang, Y Gao, W Liu, Y Shi, Y Ma - Open Medicine, 2021 - degruyter.com
Objective The purpose of this study was to explore the effect of CRABP2 and FABP5, and
their ratio on prognosis in esophageal squamous cell carcinoma. Methods The expression …

CRABP1-reduced expression is associated with poorer prognosis in serous and clear cell ovarian adenocarcinoma

T Miyake, Y Ueda, S Matsuzaki, T Miyatake… - Journal of cancer …, 2011 - Springer
Purpose CRABP1 is a modulator of retinoic acid function. The aim of the present study was
to investigate CRABP1 expression and its clinical significance in ovarian carcinoma …

High expression of FABP4 and FABP6 in patients with colorectal cancer

Y Zhang, X Zhao, L Deng, X Li, G Wang, Y Li… - World Journal of …, 2019 - Springer
Objective To explore the relationship between FABP4 and FABP6 expression and the
pathogenesis of colorectal cancer (CRC) and their potential as biomarkers in the diagnosis …

CRABP2 and FABP5 expression levels in diseased and normal pancreas

CS Hughes, JA ChinAleong, HM Kocher - Annals of Diagnostic Pathology, 2020 - Elsevier
Recently, stromal targeting, by agents such as All trans retinoic acid (ATRA), has been
regarded as a promising avenue for the treatment of pancreatic ductal adenocarcinoma …

Downregulation of CRABP2 inhibit the tumorigenesis of hepatocellular carcinoma in vivo and in vitro

Q Chen, L Tan, Z Jin, Y Liu… - BioMed research …, 2020 - Wiley Online Library
Cellular retinoic acid‐binding protein 2 (CRABP2) binds retinoic acid (RA) in the cytoplasm
and transports it into the nucleus, allowing for the regulation of specific downstream signal …

Expression and clinical significance of CRABP1 and CRABP2 in non-small cell lung cancer

I Favorskaya, Y Kainov, G Chemeris, A Komelkov… - Tumor Biology, 2014 - Springer
The impairment of retinoic acid (RA)-dependent signaling is a frequent event during
carcinogenesis. Cellular retinoic acid-binding proteins (CRABP1 and CRABP2) are …

Plasma CRABP2 as a novel biomarker in patients with non-small cell lung cancer

DJ Kim, WJ Kim, M Lim, Y Hong… - Journal of Korean …, 2018 - synapse.koreamed.org
Background Lung cancer is the most common cause of cancer-related mortality worldwide.
We previously reported the identification of a new genetic marker, cellular retinoic acid …

CRABP1 provides high malignancy of transformed mesenchymal cells and contributes to the pathogenesis of mesenchymal and neuroendocrine tumors

Y Kainov, I Favorskaya, V Delektorskaya, G Chemeris… - Cell Cycle, 2014 - Taylor & Francis
CRABP1 (cellular retinoic acid binding protein 1) belongs to the family of fatty acid binding
proteins. Retinoic acid binding is the only known functional activity of this protein. The role of …

[HTML][HTML] High expression of FABP4 in colorectal cancer and its clinical significance

Y Zhang, W Zhang, XIA Min, XIE Zhujun… - Journal of Zhejiang …, 2021 - ncbi.nlm.nih.gov
Objective To investigate the relationship between the fatty acid-binding protein 4 (FABP4)
and colorectal cancer (CRC). Methods Using an enzyme-linked immunosorbent assay …

Frequent methylation-associated silencing of a candidate tumor-suppressor, CRABP1, in esophageal squamous-cell carcinoma

K Tanaka, I Imoto, J Inoue, K Kozaki, H Tsuda… - Oncogene, 2007 - nature.com
Epigenetic alterations and the resulting inactivation of tumor suppressor genes often
contribute to the development of various cancers. To identify novel candidates that may be …