[HTML][HTML] Norwogonin attenuates hypoxia-induced oxidative stress and apoptosis in PC12 cells

L Jing, R Gao, J Zhang, D Zhang, J Shao, Z Jia… - … Medicine and Therapies, 2021 - Springer
Background Norwogonin is a natural flavone with three phenolic hydroxyl groups in skeletal
structure and has excellent antioxidant activity. However, the neuroprotective effect of …

[HTML][HTML] Protective role of wogonin following traumatic brain injury by reducing oxidative stress and apoptosis via the PI3K/Nrf2/HO‑1 pathway

Y Feng, Y Ju, Z Yan, M Ji, M Yang… - International …, 2022 - spandidos-publications.com
Traumatic brain injury (TBI) is usually caused by accidental injuries and traffic accidents,
with a very high mortality rate. Treatment and management following TBI are essential to …

Formononetin attenuates H2O2-induced cell death through decreasing ROS level by PI3K/Akt-Nrf2-activated antioxidant gene expression and suppressing MAPK …

M Sugimoto, R Ko, H Goshima, A Koike, M Shibano… - Neurotoxicology, 2021 - Elsevier
Formononetin is an isoflavone, found in herbs like Trifolium pratense, which executes a
variety of physiological activities including anti-neurodegenerative effect. However, the …

Ophiopogonin D prevents H2O2-induced injury in primary human umbilical vein endothelial cells

J Qian, F Jiang, B Wang, Y Yu, X Zhang, Z Yin… - Journal of …, 2010 - Elsevier
AIM OF THE STUDY: Vessel endothelium injury caused by reactive oxygen species (ROS)
including H2O2 plays a critical role in the pathogenesis of cardiovascular disorders …

[HTML][HTML] Monotropein alleviates H2O2-induced inflammation, oxidative stress and apoptosis via NF-κB/AP-1 signaling

F Jiang, XR Xu, WM Li, K Xia… - Molecular …, 2020 - spandidos-publications.com
Aging is a major risk factor in cardiovascular disease (CVD). Oxidative stress and
inflammation are involved in the pathogenesis of CVD, and are closely associated with …

[HTML][HTML] Xanomeline protects cortical cells from oxygen-glucose deprivation via inhibiting oxidative stress and apoptosis

R Xin, Z Chen, J Fu, F Shen, Q Zhu, F Huang - Frontiers in Physiology, 2020 - frontiersin.org
Xanomeline, a muscarinic acetylcholine receptor agonist, is one of the first compounds that
was found to be effective in the treatment of schizophrenics and attenuating behavioral …

[HTML][HTML] Methylophiopogonanone B of radix ophiopogonis protects cells from H2O2‑induced apoptosis through the NADPH oxidase pathway in HUVECs

L Wang, Y Zhou, Y Qin, Y Wang… - Molecular …, 2019 - spandidos-publications.com
Abstract Methylophiopogonanone B (MO‑B), which belongs to a group of
homoisoflavonoids, present in Ophiopogon japonicus, has been identified as an active …

Ampelopsin Inhibits H2O2‐induced Apoptosis by ERK and Akt Signaling Pathways and Up‐regulation of Heme Oxygenase‐1

X Kou, K Shen, Y An, S Qi, WX Dai… - Phytotherapy …, 2012 - Wiley Online Library
Oxidative stress plays an important role in neurodegenerative disorders. Ampelopsin, a
flavonoid abundant in Rattan tea (Ampelopsis grossedentata), is a potent antioxidant and its …

[HTML][HTML] Nobiletin alleviates astrocyte activation and oxidative stress induced by hypoxia in vitro

D Wang, F Gao, F Hu, J Wu - Molecules, 2022 - mdpi.com
Increasing evidence indicates that nobiletin (NOB) is a promising neuroprotective agent.
Astrocyte activation plays a key role in neurodegenerative disorders. Thus, this study aims to …

Alteronol induces cell cycle arrest and apoptosis via increased reactive oxygen species production in human breast cancer T47D cells

B Ren, D Li, L Si, Y Ding, J Han… - Journal of Pharmacy …, 2018 - academic.oup.com
Objective Emerging evidence showed that alteronol has a potential antitumour effect in
several tumour cells. However, the antitumour effect of alteronol on breast cancer has not …