The role of mifepristone on first trimester miscarriage treatment–A double-blind randomized controlled trial–MiFirsT

B Bettencourt-Silva, MT Rego, C Miranda… - European Journal of …, 2023 - Elsevier
Objectives To evaluate the efficacy of combined mifepristone and misoprostol compared to
misoprostol alone in outpatient medical treatment of first trimester miscarriage. Additionally …

Combination therapy with mifepristone and misoprostol for the management of first trimester miscarriage: Improved success

A Dunford, R Fyfe - Australian and New Zealand Journal of …, 2018 - Wiley Online Library
Background First trimester miscarriage affects 20% of pregnancies. Medical management
has a high degree of patient acceptance and does not increase the risk of infection …

Prospective open-label non-inferiority randomised controlled trial comparing letrozole and mifepristone pretreatment in medical management of first trimester missed …

L Du, RHW Li, K Gemzell-Danielsson, YH Du… - BMJ open, 2022 - bmjopen.bmj.com
Introduction Medical treatment is a less invasive alternative to surgical management of
missed miscarriage. Studies have shown that pretreatment with mifepristone can increase …

Comparing letrozole and mifepristone pre‐treatment in medical management of first trimester missed miscarriage: a prospective open‐label non‐inferiority …

L Du, HWR Li, K Gemzell‐Danielsson… - … Journal of Obstetrics …, 2024 - Wiley Online Library
Objective To investigate whether letrozole pre‐treatment is non‐inferior to mifepristone pre‐
treatment, followed by misoprostol, for complete evacuation in the medical treatment of first …

Mifepristone and misoprostol versus placebo and misoprostol for resolution of miscarriage in women diagnosed with missed miscarriage: the MifeMiso RCT

A Devall, J Chu, L Beeson, P Hardy, V Cheed… - Health Technology …, 2021 - ora.ox.ac.uk
Trial design A randomised, parallel-group, double-blind, placebo-controlled multicentre
study with health economic and nested qualitative studies to determine if mifepristone …

Combination of mifepristone and misoprostol vs misoprostol monotherapy for treatment of second-trimester pregnancy loss

I Valero, R Garcia-Jimenez… - … European Journal of …, 2022 - Taylor & Francis
Objective Our main goal was to evaluate whether a treatment protocol based on the
combination of mifepristone and misoprostol for second-trimester foetal loss was more …

[HTML][HTML] Mifepristone and misoprostol versus misoprostol alone for the management of missed miscarriage (MifeMiso): a randomised, double-blind, placebo-controlled …

JJ Chu, AJ Devall, LE Beeson, P Hardy, V Cheed… - The Lancet, 2020 - thelancet.com
Background The anti-progesterone drug mifepristone and the prostaglandin misoprostol can
be used to treat missed miscarriage. However, it is unclear whether a combination of …

Efficacy of mifepristone and misoprostol for medical treatment of missed miscarriage in clinical practice—a cohort study

L Ehrnstén, D Altman, A Ljungblad… - Acta Obstetricia et …, 2020 - Wiley Online Library
Introduction It has been estimated that one out of every four women experience first‐
trimester miscarriage. Missed miscarriage is a common form of early miscarriage where the …

Medical management of early fetal demise using a combination of mifepristone and misoprostol

PT Wagaarachchi, PW Ashok, N Narvekar… - Human …, 2001 - academic.oup.com
BACKGROUND: This study aims to assess the efficacy of a combination of mifepristone and
misoprostol in the management of missed miscarriage and anembryonic pregnancy …

Mifepristone and misoprostol versus misoprostol alone for uterine evacuation after early pregnancy failure: study protocol for a randomized double blinded placebo …

J van den Berg, CC Hamel, MP Snijders… - BMC pregnancy and …, 2019 - Springer
Background Early pregnancy failure (EPF) is a common complication of pregnancy. If
women do not abort spontaneously, they will undergo medical or surgical treatment in order …