Temporal increases in plasma markers of oxidized low-density lipoprotein strongly reflect the presence of acute coronary syndromes

S Tsimikas, C Bergmark, RW Beyer, R Patel… - Journal of the American …, 2003 - jacc.org
Objectives: This study was conducted to test the hypothesis that plasma markers of oxidized
low-density lipoprotein (OxLDL) reflect acute coronary syndromes (ACS). Background …

Clinical significance of antibody against oxidized low density lipoprotein in patients with atherosclerotic coronary artery disease

T Inoue, T Uchida, H Kamishirado, K Takayanagi… - Journal of the American …, 2001 - jacc.org
OBJECTIVES This study was designed to establish the clinical significance of antibodies
against oxidized low density lipoprotein (anti-Ox-LDL) titer in atherosclerotic coronary artery …

Oxidized LDL in carotid plaques and plasma associates with plaque instability

K Nishi, H Itabe, M Uno, KT Kitazato… - … , and vascular biology, 2002 - Am Heart Assoc
Objective—Oxidation of LDL plays a significant pathogenic role in atherosclerosis. In this
study, we attempted to clarify the correlation between the morphology of human …

Oxidative modification of LDL: its pathological role in atherosclerosis

H Itabe - Clinical reviews in allergy & immunology, 2009 - Springer
Oxidized low-density lipoprotein (OxLDL) is a well-known risk marker for cardiovascular
diseases. OxLDL has shown a variety of proatherogenic properties in experiments …

Elevated levels of oxidized low-density lipoprotein correlate positively with C-reactive protein in patients with acute coronary syndrome

Y Zhang, J Wei, F Wang, M Chen, M Zhang - Cell biochemistry and …, 2012 - Springer
The relationship between oxidized low-density lipoprotein (Ox-LDL) and C-reactive protein
(CRP) in patients with acute coronary syndrome (ACS) is unknown. We, therefore, measured …

Oxidation-dependent effects of oxidized LDL: proliferation or cell death

CY Han, Y Kim Pak - Experimental & molecular medicine, 1999 - nature.com
Oxidized low-density lipoprotein (oxLDL) induces a wide range of cellular responses to
produce atherosclerotic lesion, but key factors determining the response are not understood …

Impact of oxidized low density lipoprotein on vascular cells

J Galle, T Hansen-Hagge, C Wanner, S Seibold - Atherosclerosis, 2006 - Elsevier
Oxidized LDL (OxLDL) is a proatherogenic lipoprotein, accumulating in the vascular wall
and contributing to the pathogenesis of vascular dysfunction early in the development of …

Oxidized low-density lipoprotein is associated with apoptosis of vascular smooth muscle cells in human atherosclerotic plaques

Y Okura, M Brink, H Itabe, KJ Scheidegger… - Circulation, 2000 - Am Heart Assoc
Background—Cytotoxic oxidized LDL (oxLDL) has been shown to promote apoptosis in
cultured vascular smooth muscle cells (VSMCs). We investigated the localization of oxLDL …

The dynamics of oxidized LDL during atherogenesis

H Itabe, T Obama, R Kato - Journal of lipids, 2011 - Wiley Online Library
Accumulating evidence indicates that oxidized low‐density lipoprotein (OxLDL) is a useful
marker for cardiovascular disease. The uptake of OxLDL by scavenger receptors leads to …

Assessment of IgG antibodies to oxidized LDL in patients with acute coronary syndrome

R Laczik, P Szodoray, K Veres, E Szomjak, I Csípő… - Lupus, 2011 - journals.sagepub.com
Objectives. Circulating IgG antibodies to oxidized low-density lipoprotein (anti-oxLDL) have
been implicated in the development of atherosclerotic plaques. In this study, we investigated …