Dendritic cell vaccination for cancer therapy

FO Nestle - Oncogene, 2000 - nature.com
A growing list of defined tumor-antigens opens the way to antigen specific immunotherapy of
cancer. However current approaches are often limited in their potential to induce an effective …

Dendritic cell-based vaccines and therapies for cancer

T Tatsumi, WJ Storkus - Expert Opinion on Biological Therapy, 2002 - Taylor & Francis
Dendritic cells (DCs) are the most potent professional antigen-presenting cells (APCs), and
are capable of stimulating naive T cells and driving primary immune responses. Due to this …

Dendritic cells as cancer therapeutics

CE Bryant, S Sutherland, B Kong… - Seminars in Cell & …, 2019 - Elsevier
The ability of immune therapies to control cancer has recently generated intense interest.
This therapeutic outcome is reliant on T cell recognition of tumour cells. The natural function …

Dendritic cell therapy in cancer treatment; the state-of-the-art

M Sadeghzadeh, S Bornehdeli… - Life sciences, 2020 - Elsevier
Dendritic cells (DCs) are considered as professional antigen presenting cells (APCs),
containing a variety of subsets, that can be resident in organs or migrating among the …

Dendritic cells in cancer immunotherapy: vaccines and combination immunotherapies

P Kalinski, R Muthuswamy, J Urban - Expert review of vaccines, 2013 - Taylor & Francis
Dendritic cells (DCs) are specialized immunostimulatory cells involved in the induction and
regulation of immune responses. The feasibility of large-scale ex vivo generation of DCs …

Immune modulation by dendritic-cell-based cancer vaccines

C Kumar, S Kohli, PP Bapsy, AK Vaid, M Jain… - Journal of …, 2017 - Springer
The interplay between host immunity and tumour cells has opened the possibility of
targeting tumour cells by modulation of the human immune system. Cancer immunotherapy …

Dendritic cell–based immunotherapy: state of the art and beyond

KF Bol, G Schreibelt, WR Gerritsen, IJM De Vries… - Clinical cancer …, 2016 - AACR
Dendritic cell (DC) vaccination in cancer patients aims to induce or augment an effective
antitumor immune response against tumor antigens and was first explored in a clinical trial …

Genetically modified dendritic cells in cancer immunotherapy: a better tomorrow?

MR Shurin, M Gregory, JC Morris… - Expert Opinion on …, 2010 - Taylor & Francis
Importance of the field: Dendritic cells (DC) are powerful antigen-presenting cells that induce
and maintain primary cytotoxic T lymphocyte (CTL) responses directed against tumor …

Reengineering dendritic cell‐based anti‐cancer vaccines

GK Koski, PA Cohen, RE Roses, S Xu… - Immunological …, 2008 - Wiley Online Library
Despite initial enthusiasm, dendritic cell (DC)‐based anti‐cancer vaccines have yet to live
up to their promise as one of the best hopes for generating effective anti‐tumor immunity …

Molecular and cellular mechanisms of antitumor immune response activation by dendritic cells

OV Markov, NL Mironova, VV Vlasov… - Acta Naturae …, 2016 - cyberleninka.ru
Dendritic cells (DCs) play a crucial role in the initiation and regulation of the antitumor
immune response. Already, DC-based antitumor vaccines have been thoroughly explored …