S100A4/non-muscle myosin II signaling regulates epithelial-mesenchymal transition and stemness in uterine carcinosarcoma

M Tochimoto, Y Oguri, M Hashimura, R Konno… - Laboratory …, 2020 - nature.com
Uterine carcinosarcoma (UCS) represents a true example of cancer associated with
epithelial-mesenchymal transition (EMT), which exhibits cancer stem cell (CSC)-like traits …

[HTML][HTML] S100A4/nonmuscle myosin IIA/p53 axis contributes to aggressive features in ovarian high-grade serous carcinoma

A Hiruta, Y Oguri, A Yokoi, T Matsumoto, Y Oda… - The American journal of …, 2020 - Elsevier
S100A4 is a small calcium-binding protein that exerts its biological functions by interacting
with nonmuscle myosin IIA (NMIIA) and p53. Although S100A4 promotes metastasis in …

[HTML][HTML] S100A4 promotes endometrial cancer progress through epithelial-mesenchymal transition regulation

T Hua, S Liu, X Xin, L Cai, R Shi, S Chi… - Oncology …, 2016 - spandidos-publications.com
Epithelial-mesenchymal transition (EMT) is a major cause of endometrial cancer (EC) to
initiate invasion and metastasis. S100A4, a calcium-binding protein, is implicated in …

S100A4 accelerates the proliferation and invasion of endometrioid carcinoma and is associated with the “MELF” pattern

S Tahara, S Nojima, K Ohshima, Y Hori… - Cancer …, 2016 - Wiley Online Library
Endometrioid carcinoma (EC) is one of the most common malignancies of the female genital
system. Although the behavior of EC ranges from an excellent prognosis to aggressive …

Upregulation of S100A6 in patients with endometriosis and its role in ectopic endometrial stromal cells

Y Peng, J Lin, J Ma, K Lin, K Xu, J Lin - Gynecological …, 2018 - Taylor & Francis
S100 calcium-binding protein A6 (S100A6) is up-regulated in many malignancies and
overexpression of S100A6 has been identified associated with proliferation, migration and …

S100B mediates stemness of ovarian cancer stem-like cells through inhibiting p53

T Yang, J Cheng, Y Yang, W Qi, Y Zhao, H Long… - Stem …, 2017 - academic.oup.com
S100B is one of the members of the S100 protein family and is involved in the progression of
a variety of cancers. Ovarian cancer is driven by cancer stem-like cells (CSLCs) that are …

[HTML][HTML] Identification and characterization of a subpopulation of CD133+ cancer stem‐like cells derived from SK-UT-1 cells

J Gao, T Yang, X Wang, Y Zhang, J Wang… - Cancer Cell …, 2021 - Springer
Background Uterine leiomyosarcoma (ULMS) is a malignant tumor found in the smooth
muscle lining the walls of the uterus. Cancer stem cells (CSCs) are responsible for …

S100P is overexpressed in squamous cell and Adenosquamous carcinoma subtypes of endometrial Cancer and promotes Cancer cell proliferation and invasion

H Jiang, H Hu, F Lin, YP Lim, Y Hua, X Tong… - Cancer …, 2016 - Taylor & Francis
ABSTRACT S100P is known to affect tumor development and metastasis of various cancers,
but its role in endometrial cancer is unclear. We reported that S100P expression was …

[HTML][HTML] Functional interaction between S100A1 and MDM2 may modulate p53 signaling in normal and malignant endometrial cells

M Nakagawa, S Higuchi, M Hashimura, Y Oguri… - BMC cancer, 2022 - Springer
Background S100A1 expression is deregulated in a variety of human malignancies, but its
role in normal and malignant endometrial cells is unclear. Methods We used endometrial …

[HTML][HTML] S100A6 promotes the proliferation and migration of cervical cancer cells via the PI3K/Akt signaling pathway

A Li, Y Gu, X Li, H Sun, H Zha, J Xie… - Oncology …, 2018 - spandidos-publications.com
Cervical cancer is the second most common gynecological cancer worldwide and remains
one of the leading causes of cancer-associated mortality among women. S100A6 has been …