Mucosal immunity plays a crucial role in controlling upper respiratory infections, including
influenza. We established a quantitative ELISA to measure the amount of influenza virus …

Live attenuated influenza vaccine (LAIV) has demonstrated varying levels of efficacy against
seasonal influenza; however, LAIV may be used as a tool to measure interactions between …

Secretory IgAs (sIgA) constitute the principal isotype of antibodies present in nasal and
mucosal secretions. They are secreted by plasma cells adjacent to the mucosal epithelial …

Immune responses at the respiratory mucosal interface are critical to prevent respiratory
infections but it is unclear to what extent antigen specific mucosal secretory IgA (SIgA) …

Mucosal immune responses are critical to prevent respiratory infections but it is unclear to
what extent antigen specific mucosal secretory IgA (SIgA) antibodies are induced by mRNA …

While IgM and IgG response to SARS-CoV-2 has been extensively studied, relatively little is
known about secretory IgA (sIgA) response in respiratory mucosa. Here we report IgA …

Objectives: Defense against respiratory viruses depends on an immune response present in
the mucosa, as saliva IgA secretes antibodies. During the pandemic, such as influenza or …

Introduction Several novel vaccine platforms aim at mucosal immunity in the respiratory tract
to block SARS-CoV-2 transmission. Standardized methods for mucosal sample collection …

In spite of there being a number of vaccines, influenza remains a significant global cause of
morbidity and mortality. Understanding more about natural and vaccine induced immune …

Secretory IgA plays an important role in the mucosal immune system for protection against
pathogens. However, the antigens recognized by these antibodies have only been partially …