Serotonin plays a key role in the development and maintenance of the pathobiology
associated with pulmonary arterial hypertension (PAH). Platelet‐driven and locally produced …

Pulmonary arterial hypertension (PAH) is a chronic disease characterized by sustained
elevation of pulmonary arterial pressure that leads to right ventricle failure and death …

Increased synthesis of serotonin and/or activity of serotonin in pulmonary arteries has been
implicated in the pathobiology of pulmonary arterial hypertension (PAH). The incidence of …

The serotonin hypothesis of pulmonary arterial hypertension (PAH) arose owing to
anorexigens, acting as indirect serotinergic agonists, causing PAH. However, it is now …

Pulmonary arterial hypertension (PAH) is characterized by a sustained and progressive
elevation in pulmonary arterial pressure and pulmonary vascular remodelling leading to …

Summary In the 1960s, serotonin (5HT) was associated with pulmonary arterial
hypertension (PAH) caused by certain diet pills, but has recently been the subject of …

Pulmonary arterial hypertension (PAH), a condition characterized by pulmonary vasculature
constriction and remodeling, involves dysregulation of the serotonin (5-HT) receptors 5-HT …

Serotonin is often referred to as a “happy hormone” as it maintains good mood, well‐being,
and happiness. It is involved in communication between nerve cells and plays a role in …

Aims A mechanism for co-operation between the serotonin (5-hydroxytryptamine, 5-HT)
transporter and 5-HT1B receptor in mediating pulmonary artery vasoconstriction and …

Objectives: It has been reported that serotonin (5-HT) is involved in the development of
pulmonary arterial hypertension (PAH) with pulmonary vascular remodeling. The purpose of …