Assessing platelet reactivity after drug eluting stent implantation: state of the art

US Tantry, S Timilsina, A Rout, K Bliden… - Expert Review of …, 2020 - Taylor & Francis
Introduction: Platelets play a pivotal role in the occurrence of recurrent ischemic events in
coronary artery disease patients who are treated with drug-eluting stents and are on dual …

[HTML][HTML] Platelet reactivity: back to the future?

L Bonello, M Laine, C Frere - JACC: Cardiovascular Interventions, 2017 - jacc.org
Although the use of drug-eluting stents (DES) has significantly reduced the rates of ischemic
events in patients with coronary artery disease undergoing percutaneous coronary …

Is There an Ideal Level of Platelet P2Y12-Receptor Inhibition in Patients Undergoing Percutaneous Coronary Intervention? “Window” Analysis From the ADAPT-DES …

AJ Kirtane, PB Parikh, TD Stuckey, K Xu… - JACC: Cardiovascular …, 2015 - jacc.org
Objectives: This study sought to determine whether there is an ideal level of platelet
reactivity (PR) to optimize safety and efficacy within the large multicenter ADAPT-DES …

[HTML][HTML] Stent thrombosis and platelet reactivity

E Ricottini, F Mangiacapra, G Di Sciascio - Cor et Vasa, 2013 - Elsevier
Stent thrombosis (ST) is a rare but potentially life-threatening event that can occur following
percutaneous coronary intervention (PCI) with stent implantation. Several factors related to …

Impact of aspirin and clopidogrel hyporesponsiveness in patients treated with drug-eluting stents: 2-year results of a prospective, multicenter registry study

TD Stuckey, AJ Kirtane, BR Brodie… - JACC: Cardiovascular …, 2017 - jacc.org
Objectives: In this analysis of 2-year outcomes in the ADAPT-DES (Assessment of Dual
AntiPlatelet Therapy with Drug-Eluting Stents) study, the authors sought to examine the …

[HTML][HTML] High platelet reactivity affects the clinical outcomes of patients undergoing percutaneous coronary intervention

JJ Zhang, XF Gao, Z Ge, NL Tian, ZZ Liu, S Lin… - BMC cardiovascular …, 2016 - Springer
Background The association of platelet reactivity and clinical outcomes, especially stent
thrombosis, was not so clear. We sought to investigate whether high platelet reactivity affects …

Association between high platelet reactivity following dual antiplatelet therapy and ischemic events in Japanese patients with coronary artery disease undergoing …

M Nishikawa, Y Takeda, N Isomura… - … of Atherosclerosis and …, 2020 - jstage.jst.go.jp
Aim: Although high on-treatment platelet reactivity (HTPR) with dual antiplatelet therapy
(DAPT) correlates with long-term adverse outcomes in patients undergoing percutaneous …

Platelet reactivity and clinical outcomes after coronary artery implantation of drug-eluting stents (ADAPT-DES): a prospective multicentre registry study

GW Stone, B Witzenbichler, G Weisz, MJ Rinaldi… - The Lancet, 2013 - thelancet.com
Background The relation between platelet reactivity and stent thrombosis, major bleeding,
and other adverse events after coronary artery implantation of drug-eluting stents has been …

The challenge for predicting bleeding events by assessing platelet reactivity following coronary stenting

SY Choi, MH Kim, V Serebruany - International Journal of Cardiology, 2016 - Elsevier
Background Predicting future bleeding events represents an unmet medical need that will
ultimately improve outcomes during dual antiplatelet therapy (DAPT). Although low platelet …

Assessing post-treatment platelet reactivity: a focus on patient selection and setting

M Laine, C Frere, O Ronsin, M Gaubert… - Expert Review of …, 2013 - Taylor & Francis
Dual antiplatelet therapy is critical to inhibit platelet reactivity in order to prevent ischemic
reccurences in stented patients. However, studies have observed a variable blockade of the …