New genetic causes and genetic risk factors have been identified in recent years and new
technologies for genomic and postgenomic analyses (arrays, next-generation sequencing …

Male infertility represents one of the clearest examples of a complex disease with a
substantial genetic basis. Numerous male mouse models, mutation screening and …

Male infertility is a common and complex disease, manifesting as a wide range of
phenotypes, ranging from apparently normal semen parameters with an inexplicable …

A male factor is involved in 50% of couples with infertility. Unfortunately, the etiology of male
factor infertility remains classified as idiopathic in nearly 50% of cases. The semen analysis …

Abstract Infertility affects 8%–12% of couples worldwide with a male factor contributing to
nearly 50% of couples either as a primary or contributing cause. Several genetic factors that …

Infertility is a reproductive health problem that affects many couples in the human
population. About 13–18% of couple suffers from it and approximately one-half of all cases …

Infertility is a major reproductive health problem affecting 10% to 15% of couples, with
approximately equal contributions. Spermatogenesis is a dynamic and multistep process of …

Many genetic polymorphisms have been studied extensively to elucidate their role in the
pathophysiology of male infertility. This article presents a review of the literature following a …

Introduction Thousands of genes are implicated in spermatogenesis, testicular development
and endocrine regulation of testicular function. The genetic contribution to male infertility is …

Infertility is defined as the inability to conceive after at least 12 months of regular,
unprotected sexual intercourse and it is considered an alarming global health issue. More …