TRIM35 functions as a novel tumor suppressor in breast cancer by inducing cell apoptosis through ubiquitination of PDK1.

W Rong, KL Huang, X Lian-Xiang - Neoplasma, 2022 - search.ebscohost.com
Breast cancer is the most common cancer in women. Novel mechanisms and targets are
urgently needed to understand and treat this disease due to the complexity of breast cancer …

[HTML][HTML] TRIM32 promotes proliferation and confers chemoresistance to breast cancer cells through activation of the NF-κB pathway

TT Zhao, F Jin, JG Li, YY Xu, HT Dong, Q Liu… - Journal of …, 2018 - ncbi.nlm.nih.gov
Dysregulation of TRIM32 has been implicated in several human cancers, however, its
clinical significance and biological function in breast cancer have not been investigated …

TRIM59 overexpression correlates with poor prognosis and contributes to breast cancer progression through AKT signaling pathway

Y Liu, Y Dong, L Zhao, L Su, K Diao… - Molecular …, 2018 - Wiley Online Library
TRIM59 has been recently implicated in the carcinogenesis of several cancers such as lung
cancer, gastric cancer, and bladder cancer. However, its expression pattern and clinical …

[HTML][HTML] TRIM14 promotes breast cancer cell proliferation by inhibiting apoptosis

G Hu, W Pen, M Wang - Oncology Research, 2019 - ncbi.nlm.nih.gov
Abstract Tripartite motif-containing 14 (TRIM14) is abnormally expressed in several human
cancers. However, the function and expression of TRIM14 in human breast cancer are still …

Decreased expression of TRIM21 indicates unfavorable outcome and promotes cell growth in breast cancer

W Zhou, Y Zhang, C Zhong, J Hu, H Hu… - Cancer management …, 2018 - Taylor & Francis
Background Tripartite motif-containing protein 21 (TRIM21), an E3 ubiquitin ligase, has been
implicated in autoimmune diseases. Dysregulation of TRIM21 contributes to the progression …

[HTML][HTML] TRIM35 ubiquitination regulates the expression of PKM2 tetramer and dimer and affects the malignant behaviour of breast cancer by regulating the Warburg …

H Wu, X Guo, Y Jiao, Z Wu, Q Lv - … Journal of Oncology, 2022 - spandidos-publications.com
Breast cancer has become the leading cause of death in females. After comprehensive
treatment, the lives of patients are still threatened by tumor metastasis and recurrence …

Knockdown of TRIM47 inhibits breast cancer tumorigenesis and progression through the inactivation of PI3K/Akt pathway

Y Wang, C Liu, Z Xie, H Lu - Chemico-biological interactions, 2020 - Elsevier
Tripartite motif (TRIM) protein family is a group of proteins, which belongs to RING family of
ubiquitin E3 ligases. TRIM proteins are involved in oncogenesis, while the roles in different …

[HTML][HTML] Loss of TRIM31 promotes breast cancer progression through regulating K48-and K63-linked ubiquitination of p53

Y Guo, Q Li, G Zhao, J Zhang, H Yuan, T Feng… - Cell death & …, 2021 - nature.com
Breast cancer is the most common cancer in the world. Relapse and metastasis are
important factors endangering the life of breast cancer patients, but the mechanism is still …

[HTML][HTML] TRIM3 inhibits P53 signaling in breast cancer cells

X Wang, Y Zhang, X Pei, G Guo, B Xue, X Duan… - Cancer cell …, 2020 - Springer
Background Beast cancer is the most common women cancer worldwide, while two third of
them are ER alpha positive breast cancer. Among the ER alpha positive breast cancer …

[HTML][HTML] Tripartite motif‑containing 11 regulates the proliferation and apoptosis of breast cancer cells

X Dai, F Geng, M Li, M Liu - Oncology reports, 2019 - spandidos-publications.com
Breast cancer, an increasing health problem worldwide, is the second major cause of cancer‑
associated mortality in females. Studies have focused on the pathogenesis of breast cancer …