Oral drug delivery is considered the most preferred mode of treatment because of its high
patient compliance and minimal invasiveness. However, the oral delivery of protein drug has …

To overcome barriers for oral delivery of insulin, the chitosan (CS)-based nanocarriers with a
novel cell penetrating peptide (SAR6EW) have been prepared and evaluated in this study …

Polymeric nanoparticles have been widely applied to oral delivery of protein drugs,
however, few studies focused on the systematical elucidation of the size-dependent oral …

The feasibility of combining safe permeation enhancers in a mucoadhesive particulate
system for the oral delivery of peptide drugs was investigated in this study. Polyelectrolyte …

In spite of several intrinsic and distinct advantages, a topical and transdermal administration
of drugs has been limited mainly due to very low permeability of drugs across skin …

Mucus is a viscoelastic hydrogel that lubricates and protects mucosal tissues such as the
eyes, lung, gastrointestinal tract, and vagina. Nanoparticle-based drug delivery systems …

Peptide (insulin) loaded nanoparticles (NPs) have been embedded into buccal chitosan
films (Ch-films-NPs). These films were produced by solvent casting and involved …

Mucosal administration of drugs and drug delivery systems has gained increasing interest.
However, nanoparticles intended to protect and deliver drugs to epithelial surfaces require …

A pH-sensitive nanoparticle (NP) system composed of chitosan and poly (γ-glutamic acid)
was prepared for the oral delivery of insulin. The biodistribution study in a rat model showed …

In this work a novel chitosan derivative, lauryl succinyl chitosan (LSC) was developed for the
purpose of evaluating its applications towards oral peptide delivery system …