Looking at the Pathogenesis of the Rabies Lyssavirus Strain Pasteur Vaccins through a Prism of the Disorder-Based Bioinformatics
S Dhulipala, VN Uversky - Biomolecules, 2022 - mdpi.com
Rabies is a neurological disease that causes between 40,000 and 70,000 deaths every
year. Once a rabies patient has become symptomatic, there is no effective treatment for the …
year. Once a rabies patient has become symptomatic, there is no effective treatment for the …
Intrinsic Disorder in the Host Proteins Entrapped in Rabies Virus Particles
HN Ashraf, VN Uversky - Viruses, 2024 - mdpi.com
A proteomics analysis of purified rabies virus (RABV) revealed 47 entrapped host proteins
within the viral particles. Out of these, 11 proteins were highly disordered. Our study was …
within the viral particles. Out of these, 11 proteins were highly disordered. Our study was …
Quantitative proteomics leads to identify dog brain proteins involved in rabies virus infection: implication in understanding viral pathophysiology
S Behera, RR Pharande, RR Reddy, SB Majee… - Journal of Proteins and …, 2020 - Springer
Rabies is a neglected tropical disease caused by the rabies virus (RABV) and it is mostly
transmitted to humans by dogs. However, knowledge about host factors and their role in …
transmitted to humans by dogs. However, knowledge about host factors and their role in …
[PDF][PDF] Large protein as a potential target for use in rabies diagnostics
ISS Katz, MH Dias, IF Lima, LB Chaves, OG Ribeiro… - Acta Virol, 2017 - academia.edu
Rabies is a zoonotic viral disease that remains a serious threat to public health worldwide.
The rabies lyssavirus (RABV) genome encodes five structural proteins, multifunctional and …
The rabies lyssavirus (RABV) genome encodes five structural proteins, multifunctional and …
Japanese encephalitis virus–exploring the dark proteome and disorder–function paradigm
Japanese encephalitis virus (JEV) is one of the major causes of viral encephalitis all around
the globe. Approximately 3 billion people in endemic areas are at risk of Japanese …
the globe. Approximately 3 billion people in endemic areas are at risk of Japanese …
Structural disorder in the proteome and interactome of Alkhurma virus (ALKV)
Infection by the Alkhurma virus (ALKV) leading to the Alkhurma hemorrhagic fever is a
common thread in Saudi Arabia, with no efficient treatment or prevention available as of yet …
common thread in Saudi Arabia, with no efficient treatment or prevention available as of yet …
Exploring the conformational landscape of the rabies virus glycoprotein using HDX-MS
Rabies virus, a member of the lyssavirus family, causes on the order of 60,000 deaths per
year, disproportionately affecting historically exploited regions of the world. While …
year, disproportionately affecting historically exploited regions of the world. While …
Comprehensive intrinsic disorder analysis of 6108 viral proteomes: from the extent of intrinsic disorder penetrance to functional annotation of disordered viral proteins
Much of our understanding of proteins and proteomes comes from the traditional protein
structure–function paradigm. However, in the last 2 decades, both computational and …
structure–function paradigm. However, in the last 2 decades, both computational and …
Insights into the evolutionary forces that shape the codon usage in the viral genome segments encoding intrinsically disordered protein regions
Intrinsically disordered regions/proteins (IDRs) are abundant across all the domains of life,
where they perform important regulatory roles and supplement the biological functions of …
where they perform important regulatory roles and supplement the biological functions of …
Systems biomedicine of rabies delineates the affected signaling pathways
S Azimzadeh Jamalkandi, SH Mozhgani… - Frontiers in …, 2016 - frontiersin.org
The prototypical neurotropic virus, rabies, is a member of the Rhabdoviridae family that
causes lethal encephalomyelitis. Although there have been a plethora of studies …
causes lethal encephalomyelitis. Although there have been a plethora of studies …