The history of direct cell-cell communication has evolved in several small steps. First
discovered in the 1930s in invertebrate nervous systems, it was thought at first to be an …

Intercellular communications play a major role in tissue homeostasis and responses to
external cues. Novel structures for this communication have recently been described. These …

Depending on their tissue of origin, genetic and epigenetic marks and microenvironmental
influences, cancer cells cover a broad range of metabolic activities that fluctuate over time …

Coordinated interaction of single cells by cell-to-cell communication (signalling) enables
complex behaviour necessary for the functioning of multicellular organisms. A quite newly …

A century ago, the Warburg effect was first proposed, revealing that cancer cells
predominantly rely on glycolysis during the process of tumorigenesis, even in the presence …

Intercellular communications play a major role in tissue homeostasis. In pathologies such as
cancer, cellular interactions within the tumor microenvironment (TME) contribute to tumor …

Mitochondria are commonly perceived as “cellular power plants”. Intriguingly, power
conversion is not their only function. In the first part of this paper, we review the role of …

Cancer progresses by evading the immune system. Elucidating diverse immune evasion
strategies is a critical step in the search for next-generation immunotherapies for cancer …

Our vision of cancer has changed during the past decades. Indeed tumors are now
perceived as complex entities where tumoral and stromal components interact closely …

Mitochondria communicate with the rest of the cell through channels located in their inner
and outer membranes. Most of the time, the message is encoded by the flow of anions and …