Rhinoviruses (RVs) evoke as many as 85% of acute asthma exacerbations in children and
50% in adults and can induce airway hyperresponsiveness and decrease efficacy of current …

Rhinovirus (RV) exposure evokes exacerbations of asthma that markedly impact morbidity
and mortality worldwide. The mechanisms by which RV induces airway …

Remember the smooth muscle cell? Most cases of asthma are due to allergic inflammation.
Inflammatory cells release pro-inflammatory cytokines and other mediators which induce …

Background: Rhinovirus (RV), the principal pathogen responsible for the common cold, is
importantly implicated in triggering attacks of asthma secondary to changes in airway …

Background Rhinovirus infections commonly evoke asthma exacerbations in children and
adults. Recurrent asthma exacerbations are associated with injury-repair responses in the …

An important interplay exists between specific viral respiratory pathogens, most commonly
rhinovirus (RV), and altered airway responsiveness in the development and exacerbations …

Rhinovirus (RV) exposure has been implicated in childhood development of wheeze
evoking asthma and exacerbations of underlying airways disease. Studies such as the …

Rhinovirus (RV) infections trigger exacerbations of airways disease, but underlying
mechanisms remain unknown. We hypothesized that RV and cytokines present in inflamed …

The airway responses to allergen exposure in allergic asthma are qualitatively similar to
those elicited by specific viral respiratory pathogens, most notably rhinovirus (RV) …

Human rhinovirus (RV) is a major risk factor for chronic obstructive pulmonary disease
(COPD) and asthma exacerbations. The exploration of RV pathogenesis has been …