Introduction Little is known about how antecedent vascular risk factor (VRF) profiles impact
late‐life brain health. Methods We examined baseline VRFs, and cognitive testing and …

Objective Midlife vascular risk factors (MVRFs) are associated with incident dementia, as are
amyloid β (Aβ) deposition and neurodegeneration. Whether vascular and Alzheimer disease …

The involvement of vascular factors in Alzheimer dementia was first appreciated over 100
years ago. Recently, significant advances in our understanding of these brain‐vascular …

Background: Vascular disease is associated with increased risk of dementia. Vascular
health worsens with age. We investigated the relationship between self-reported vascular …

Objective To determine whether vascular risk and Alzheimer disease (AD) biomarkers have
independent or synergistic effects on cognitive decline and whether vascular risk is …

Importance Identifying asymptomatic individuals at high risk of impending cognitive decline
because of Alzheimer disease is crucial for successful prevention of dementia. Vascular risk …

Objective To determine whether vascular and neurodegenerative factors influence cognition
before clinically relevant Alzheimer disease pathology, we analyzed MRI measures and …

Background: Midlife cardiovascular risk factors increase risk for Alzheimer's disease (AD).
Despite disproportionately high cardiovascular disease and dementia rates, African …

Cortical atrophy and brain vascular disease are both associated with dementia, but there are
only limited pathological data on the association of brain vascular disease with cortical …

We investigated the relationship between vascular disease and risk factors versus cognitive
decline cross-sectionally and longitudinally in normal older control, mild cognitive …