Alzheimer's disease (AD) is the most common origin of dementia in the elderly. Although the
cause of AD remains unknown, several factors have been identified that appear to play a …

This review describes several transgenic mouse models of Alzheimer's disease (AD), a
devastating neurodegenerative disorder that causes progressive cognitive decline and is …

Transgenic mice models for Alzheimer's disease (AD) are essential to the understanding of
disease pathophysiology, develop robust behavioral models and predict outcomes from …

Although great advances in elucidating the molecular basis and pathogenesis of
Alzheimer's disease (AD) have been made and multifarious novel therapeutic approaches …

Since their initial generation in the mid 1990s, transgenic mouse models of Alzheimers′ s
disease (AD) have been proven to be valuable model systems which are indispensable for …

Alzheimer disease is the most common cause of dementia among the elderly, accounting
for∼ 60-70% of all cases of dementia. The neuropathological hallmarks of Alzheimer …

Progress in understanding and treating Alzheimer's disease (AD) has been tremendously
bolstered by the era of transgenic models of AD. The identification of disease-causing …

The prevalence of neurodegenerative diseases, particularly those that affect the aged, are
predicted to increase rapidly in the coming decades. The World Health Organization …

▪ Abstract Alzheimer's disease (AD), the most common dementing disorder of late life, is a
major cause of disability and death in the elderly. Neurobiological, genetic, and molecular …

Alzheimer's disease (AD), the leading cause of dementia, presents a significant global
health challenge with no known cure to date. Central to our understanding of AD …