Purpose There is limited clinical data for recommendations on how to deliver thoracic
radiation therapy (TRT) concurrently with chemotherapy in limited-stage small cell lung …

8512 Background: Concurrent chemotherapy and TRT is standard treatment of LS SCLC.
BID TRT of 45 Gy/30 fractions is the most recommended schedule. Trials report 5-year …

Purpose/Objective (s) The Intergroup randomized controlled trial (RCT) established 45 Gy in
30 fractions (F) twice-daily (BID) as the standard thoracic radiation therapy (TRT) regimen …

The optimal integration of thoracic radiation therapy with systemic chemotherapy in the
treatment of limitedstage small-cell lung cancer remains to be defined. Although there are …

Introduction Thoracic radiotherapy (TRT) is standard of care for limited-stage small cell lung
cancer (LS-SCLC). Although initial data supported the use of twice-daily (BID) radiation to a …

7163 Background: The primary goal of the phase I portion of this trial was to identify the
maximum tolerable dose (MTD) of TRT that can be given concurrently with etoposide (E) …

Purpose: The purpose of RTOG 97–12 was to determine the maximum tolerated dose (MTD)
of thoracic radiation therapy (RT) with concurrent chemotherapy for patients with limited …

Although meta-analysis of randomized trials comparing chemotherapy alone versus
chemotherapy plus thoracic irradiation demonstrated that thoracic radiotherapy reduced …

There is a general agreement that patients with limited small cell lung cancer (L-SCLC) are
better treated with a combination of thoracic radiation therapy (TRT) and systemic …

7004 Background: Concurrent thoracic radiotherapy (TRT) with chemotherapy has been
regarded as optimal treatment for limited-disease small cell lung cancer (SCLC). However …