[HTML][HTML] Is there a place for optimizing thoracic radiotherapy in limited-stage small cell lung cancer after twenty years?

JM Barros, MM Rizzo, JO Chiozza… - World Journal of Clinical …, 2021 - ncbi.nlm.nih.gov
Thoracic radiotherapy (TRT) is one of the main treatments in limited-stage small cell lung
cancer (LS-SCLC). Hyperfractionated TRT (45 Gy, 1.5 Gy twice daily) has been the standard …

Radiation dose and fractionation for limited-stage small-cell lung cancer: survey of US radiation oncologists on practice patterns

MJ Farrell, JB Yahya, C Degnin, Y Chen, JM Holland… - Clinical lung cancer, 2019 - Elsevier
Background Thoracic radiotherapy (TRT) with concurrent chemotherapy is standard for
limited-stage small-cell lung cancer (LS-SCLC). However, the optimal dosing and …

Timing of thoracic radiation therapy with chemotherapy in limited-stage small-cell lung cancer: survey of US radiation oncologists on current practice patterns

MJ Farrell, JB Yahya, C Degnin, Y Chen, JM Holland… - Clinical Lung Cancer, 2018 - Elsevier
Introduction For limited-stage small-cell lung cancer (LS-SCLC), National Comprehensive
Cancer Network guidelines recommend that thoracic radiotherapy (TRT) be delivered …

Radiotherapy in small-cell lung cancer

H Husain, MD Christine Hann, R Hales - Oncology, 2010 - search.proquest.com
The optimal administration of radiotherapy depends on several factors, including timing
(concurrent vs sequential, early vs late), dose, fractionation, and volume of radiotherapy.[3] …

Once vs. twice daily thoracic irradiation in limited stage small cell lung cancer

JS Kim, JS Kim, JO Kim, SY Kim… - Radiation Oncology …, 1998 - koreascience.kr
Purpose: A retrospective study was conducted comparing single daily fraction (SDF) thoracic
radiotherapy (TRT) with twice daily (BID) TRT to determine the potential benefit of BID TRT …

Timing of thoracic radiotherapy is more important than dose intensification in patients with limited-stage small cell lung cancer: a parallel comparison of two …

X Hu, X Bing, Y Bao, X Yu-jin, J Wang… - Strahlentherapie …, 2020 - search.proquest.com
Purpose The optimal radiotherapy dose/fraction for limited-stage small cell lung cancer
(SCLC) is undefined. Our objectives were to compare efficacy between hyperfractionated …

Phase I study to determine the maximum-tolerated dose of radiation in standard daily and hyperfractionated-accelerated twice-daily radiation schedules with …

NC Choi, JE Herndon 2nd, J Rosenman… - Journal of clinical …, 1998 - ascopubs.org
PURPOSE An improvement in radiation dose schedule is necessary to increase local tumor
control and survival in limited-stage small-cell lung cancer. The goal of this study was to …

[HTML][HTML] Duration of twice-daily thoracic radiotherapy and time from the start of any treatment to the end of chest irradiation as significant predictors of outcomes in …

M Morimoto, K Okishio, M Akira, N Omachi, A Tamiya… - Clinical Lung Cancer, 2017 - Elsevier
Background The hypothesis of this retrospective study was that the duration of twice-daily
(BID) thoracic radiotherapy (TRT) and time from the start of any treatment to the end of chest …

Impact of total thoracic radiation dose and dose fractionation on overall survival in limited-disease small cell lung cancer: A retrospective study on 456 patients

I Wzietek, E Nowara, R Suwinski - International Journal of Radiation …, 2011 - redjournal.org
Results The differences in OS between the groups were highly significant (p= 0.0009) with 3-
year actuarial survival of 25%, 15%, 12% and 5% in groups B (hyperfractionation), D (high …

Routine use of approximately 60 Gy once-daily thoracic irradiation for patients with limited-stage small-cell lung cancer

KL Miller, LB Marks, GS Sibley, RW Clough… - International Journal of …, 2003 - Elsevier
PURPOSE: To review the outcome of patients with limited-stage small-cell lung cancer
receiving daily thoracic irradiation (RT) to approximately 60 Gy. METHODS AND …