FABP 4 is associated with inflammatory markers and metabolic syndrome in morbidly obese women

X Terra, Y Quintero, T Auguet, JA Porras… - European Journal of …, 2011 - academic.oup.com
Objective The adipocyte/macrophage fatty acid-binding protein 4 (FABP4) has been
described as a biomarker for adiposity and metabolic syndrome (MS). The aims of this study …

[HTML][HTML] FABP4 Dynamics in Obesity: Discrepancies in Adipose Tissue and Liver Expression Regarding Circulating Plasma Levels

MI Queipo-Ortuño, X Escoté, V Ceperuelo-Mallafré… - PLoS …, 2012 - journals.plos.org
Background FABP4 is predominantly expressed in adipose tissue, and its circulating levels
are linked with obesity and a poor atherogenic profile. Objective In patients with a wide BMI …

Exogenous FABP4 interferes with differentiation, promotes lipolysis and inflammation in adipocytes

HX Dou, T Wang, HX Su, DD Gao, YC Xu, YX Li… - Endocrine, 2020 - Springer
Purpose Fatty acid binding protein 4 (FABP4) has been demonstrated to be secreted from
adipocytes in an unconventional pathway associated with lipolysis. Circulating FABP4 is …

Plasma fatty acid-binding protein 4 (FABP4) as a novel biomarker to predict gestational diabetes mellitus

H Ning, H Tao, Z Weng, X Zhao - Acta diabetologica, 2016 - Springer
Aims Fatty acid-binding protein 4 (FABP4) is mainly expressed in adipocytes and
macrophages and is demonstrated to be elevated in diabetes patients. The aim of this study …

[HTML][HTML] Associations between fatty acid-binding protein 4–A proinflammatory adipokine and insulin resistance, gestational and type 2 diabetes mellitus

M Trojnar, J Patro-Małysza, Ż Kimber-Trojnar… - Cells, 2019 - mdpi.com
There is ample scientific evidence to suggest a link between the fatty acid-binding protein 4
(FABP4) and insulin resistance, gestational (GDM), and type 2 (T2DM) diabetes mellitus …

Fatty acid binding protein 4 is increased in metabolic syndrome and with thiazolidinedione treatment in diabetic patients

A Cabre, I Lazaro, J Girona, JM Manzanares… - Atherosclerosis, 2007 - Elsevier
OBJECTIVE: To study the role of FABP4 in the plasma of type 2 diabetic (T2D) subjects with
and without metabolic syndrome (MS) and the impact of thiazolidinedione (TZD) treatment …

Expression and regulation of adipocyte fatty acid binding protein in granulosa cells and its relation with clinical characteristics of polycystic ovary syndrome

W Hu, J Qiao - Endocrine, 2011 - Springer
Increased expression of adipocyte fatty acid binding protein (FABP4) is associated with type
2 diabetic, high triglycerides, increased lipid peroxidation, and inflammation markers. To …

[HTML][HTML] Serum fatty acid-binding protein 4 (FABP4) concentration is associated with insulin resistance in peripheral tissues, A clinical study

R Nakamura, T Okura, Y Fujioka, K Sumi… - PloS one, 2017 - journals.plos.org
Type 2 diabetes mellitus (T2DM) is caused by insulin resistance and β cell dysfunction. In
recent studies reported that several markers associated with insulin sensitivity in skeletal …

Fatty acid-binding protein 4 (FABP4): pathophysiological insights and potent clinical biomarker of metabolic and cardiovascular diseases

M Furuhashi, S Saitoh… - Clinical medicine …, 2014 - journals.sagepub.com
Over the past decade, evidences of an integration of metabolic and inflammatory pathways,
referred to as metaflammation in several aspects of metabolic syndrome, have been …

[HTML][HTML] Reduction of circulating FABP4 level by treatment with omega-3 fatty acid ethyl esters

M Furuhashi, S Hiramitsu, T Mita, A Omori… - Lipids in health and …, 2016 - Springer
Background Fatty acid-binding protein 4 (FABP4/A-FABP/aP2) mainly expressed in
adipocytes is secreted and acts as an adipokine. Increased circulating FABP4 level is …