From Copper Tolerance to Resistance in Pseudomonas aeruginosa towards Patho-Adaptation and Hospital Success

M Virieux-Petit, F Hammer-Dedet, F Aujoulat… - Genes, 2022 - mdpi.com
The hospital environment constitutes a reservoir of opportunistic pathogens responsible for
healthcare-associated infections (HCAI) such as Pseudomonas aeruginosa (Pa). Pa …

Copper resistance of the emerging pathogen Acinetobacter baumannii

CL Williams, HM Neu, JJ Gilbreath… - Applied and …, 2016 - Am Soc Microbiol
Acinetobacter baumannii is an important emerging pathogen that is capable of causing
many types of severe infection, especially in immunocompromised hosts. Since A …

Genomic characterization of a local epidemic Pseudomonas aeruginosa reveals specific features of the widespread clone ST395

M Petitjean, D Martak, A Silvant… - Microbial …, 2017 - microbiologyresearch.org
Pseudomonas aeruginosa is a ubiquitous opportunistic pathogen with several clones being
frequently associated with outbreaks in hospital settings. ST395 is among these so-called …

The Role of the CopA Copper Efflux System in Acinetobacter baumannii Virulence

SF Alquethamy, M Khorvash, VG Pederick… - International journal of …, 2019 - mdpi.com
Acinetobacter baumannii has emerged as one of the leading causative agents of
nosocomial infections. Due to its high level of intrinsic and adapted antibiotic resistance …

Characterization of Acinetobacter baumannii Copper Resistance Reveals a Role in Virulence

CL Williams, HM Neu, YA Alamneh… - Frontiers in …, 2020 - frontiersin.org
Acinetobacter baumannii is often highly drug-resistant and causes severe infections in
compromised patients. These infections can be life threatening due to limited treatment …

Quorum-Sensing Regulation of a Copper Toxicity System in Pseudomonas aeruginosa

JT Thaden, S Lory, TS Gardner - Journal of bacteriology, 2010 - Am Soc Microbiol
ABSTRACT The LasR/LasI quorum-sensing system in Pseudomonas aeruginosa influences
global gene expression and mediates pathogenesis. In this study, we show that the quorum …

Advances in Understanding of the Copper Homeostasis in Pseudomonas aeruginosa

L Hofmann, M Hirsch, S Ruthstein - International journal of molecular …, 2021 - mdpi.com
Thirty-five thousand people die as a result of more than 2.8 million antibiotic-resistant
infections in the United States of America per year. Pseudomonas aeruginosa (P …

Essential Gene Clusters Involved in Copper Tolerance Identified in Acinetobacter baumannii Clinical and Environmental Isolates

R Thummeepak, R Pooalai, C Harrison, L Gannon… - Pathogens, 2020 - mdpi.com
Copper is widely used as antimicrobial in agriculture and medicine. Copper tolerance
mechanisms of pathogenic bacteria have been proven to be required for both copper …

Survival and Growth in the Presence of Elevated Copper: Transcriptional Profiling of Copper-Stressed Pseudomonas aeruginosa

GM Teitzel, A Geddie, SK De Long… - Journal of …, 2006 - Am Soc Microbiol
Transcriptional profiles of Pseudomonas aeruginosa exposed to two separate copper stress
conditions were determined. Actively growing bacteria subjected to a pulse of elevated …

[HTML][HTML] Mutations in the cueA gene encoding a copper homeostasis P-type ATPase reduce the pathogenicity of Pseudomonas aeruginosa in mice

WR Schwan, P Warrener, E Keunz, CK Stover… - International Journal of …, 2005 - Elsevier
A sequencing project identified a putative copper homeostasis gene, cueA, in Pseudomonas
aeruginosa strain PAO1. Strains with mutations of the cueA gene, encoding a P-type …