Background Neuroblastoma, mainly affecting children, is a lethal malignancy arising from
the developing sympathetic nervous system. The genetic etiology of neuroblastoma remains …

Background Glioma is a malignant central nervous system tumor in children, with poor
outcomes and prognosis. HMGA2 is a proto-oncogene with increased expression in various …

Background Hepatoblastoma is a rare disease. Its etiology remains obscure. No
epidemiological reports have assessed the relationship of High Mobility Group A2 (HMGA2) …

A genetic polymorphism (rs968697 T> C) in the HMGA2 gene has recently been linked to an
increased risk of hepatoblastoma. However, no studies have been conducted to investigate …

Wilms tumor is a kidney malignancy that typically occurs in children. Aberrant expression of
HMGA2 gene is commonly seen in many malignant tumors. Yet, HMGA2 gene …

Background Neuroblastoma is one of the most common extracranial malignant solid tumors
in children. AlkB homolog 5 (ALKBH5) is an RNA N6‐methyladenosine (m6A) demethylase …

Neuroblastoma is a highly malignant extracranial solid tumor in pediatrics. ALKBH1 as a
recently discovered DNA N6-methyldeoxyadenosine (6mA) demethylase closely links to …

Background HMGA2 can promote the development of multiple malignancies. This study
aimed to determine whether a putative functional genetic polymorphism (rs968697 T> C) in …

Neuroblastoma is a lethal tumor of the sympathetic nervous system. 8-
Hydroxydeoxyguanine (8-OH-dG) formation is a common seen type of oxidative DNA …

BACKGROUND Neuroblastoma is the most frequently diagnosed extracranial solid tumor in
children. Previous studies have shown that single‐nucleotide polymorphisms in some genes …