Abstract the Intracellular Distribution Of A Specific Protein Is Essential For Its Function.
Proper Protein Localization Is Therefore An Essential Biological Process, Regulated At …

The subcellular locations of proteins are closely related to their function and constitute an
essential aspect for understanding the complex machinery of living cells. A systematic effort …

Proteomics seeks the systematic and comprehensive understanding of all aspects of
proteins, and location proteomics is the relatively new subfield of proteomics concerned with …

The eukaryotic cell is compartmentalized into subcellular niches, including membrane-
bound and membrane-less organelles. Proteins localize to these niches to fulfil their …

Localisation and sequestration of proteins within subcellular niches is a fundamental
mechanism for the post-translational regulation of protein function. Some such …

The steady-state localisation of proteins provides vital insight into their function. These
localisations are context specific with proteins translocating between different subcellular …

Information on protein localization on the subcellular level is important to map and
characterize the proteome and to better understand cellular functions of proteins. Here we …

LOCATE is a curated, web-accessible database that houses data describing the membrane
organization and subcellular localization of mouse and human proteins. Over the past 2 …

Accurate knowledge of the intracellular location of proteins is important for numerous areas
of biomedical research including assessing fidelity of putative protein-protein interactions …

As proteins within cells are spatially organized according to their role, knowledge about
protein localization gives insight into protein function. Here, we describe the LOPIT …