The human cytochrome P450 (CYP) superfamily includes at least 57 genes that encode
enzymes with diverse metabolic and biosynthetic functions. This study was conducted in …

Abstract Background Cytochrome P450 (CYP) 2C19 is a very important drug metabolizing
enzyme. Although the single nucleotide polymorphisms (SNPs) of CYP2C19 G681A and …

Background and purpose: Ischemic stroke (IS) is the main cause of mortality and disability
among the old people in China and is a multifactorial disease influenced by many factors …

Stroke is a major cause of morbidity and mortality worldwide. Genetic and environmental
factors are involved in the pathogenesis of stroke. Hypertension, diabetes mellitus, and …

Objective: The present study aims to investigate the relationship between CYP2J2 gene
polymorphisms and ischemic stroke (IS) in a Chinese Han population. Methods: We …

Objective: To conduct a meta-analysis for the correlation between cytochrome P450 4F2
(CYP4F2) rs2108622 (V433M) gene polymorphism and ischemic stroke. Methods: We …

Background The association between aldosterone synthase (CYP11B2) C-344T gene
polymorphism and ischemic stroke remains controversial and ambiguous. To better explain …

Objectives Ischemic stroke (IS) is the major cause of death and disability. While previous
studies confirmed that CYP11B1 is closely associated with IS, the present study aimed to …

Aims Ischemic stroke (IS) is a multifactorial disease caused by a combination of
environmental risk factors and genetic susceptibilities. However, few studies have assessed …

Aim: Ischemic stroke (IS) is a multifactorial disease caused by environmental risk factors and
genetic susceptibility. However, few studies have assessed whether gene–gene interactions …