Adiponectin gene polymorphism is selectively associated with the concomitant presence of metabolic syndrome and essential hypertension

HB Leu, CM Chung, SJ Lin, YS Jong, WH Pan… - PloS one, 2011 - journals.plos.org
Objective Cardiovascular risk increases with the presence of both metabolic syndrome
(MetS) and hypertension (HTN). Although the adiponectin (ADIPOQ) gene has been …

An SNP in the adiponectin gene is associated with decreased serum adiponectin levels and risk for impaired glucose tolerance

JL González‐Sánchez, CA Zabena… - Obesity …, 2005 - Wiley Online Library
Adiponectin is a plasma protein produced by the adipose tissue. Hypoadiponectinemia has
been associated with insulin resistance and several components of the metabolic syndrome …

Deep Resequencing Unveils Genetic Architecture of ADIPOQ and Identifies a Novel Low-Frequency Variant Strongly Associated With Adiponectin Variation

LL Warren, L Li, MR Nelson, MG Ehm, J Shen… - Diabetes, 2012 - Am Diabetes Assoc
Increased adiponectin levels have been shown to be associated with a lower risk of type 2
diabetes. To understand the relations between genetic variation at the adiponectin-encoding …

A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2

Y Wu, H Gao, H Li, Y Tabara… - Human molecular …, 2014 - academic.oup.com
Blood levels of adiponectin, an adipocyte-secreted protein correlated with metabolic and
cardiovascular risks, are highly heritable. Genome-wide association (GWA) studies for …

Early Detrimental Metabolic Outcomes of rs17300539‐A Allele of ADIPOQ Gene Despite Higher Adiponectinemia

A Morandi, C Maffeis, S Lobbens, N Bouatia‐Naji… - …, 2010 - Wiley Online Library
Minor allele A of single‐nucleotide polymorphism (SNP) 11391 G/A of ADIPOQ gene
(rs17300539) has been consistently associated with higher adiponectin levels in adults and …

Association of ADIPOQ gene variants with body weight, type 2 diabetes and serum adiponectin concentrations: the Finnish Diabetes Prevention Study

N Siitonen, L Pulkkinen, J Lindström… - BMC medical …, 2011 - Springer
Background Adiponectin, secreted mainly by mature adipocytes, is a protein with insulin-
sensitising and anti-atherogenic effects. Human adiponectin is encoded by the ADIPOQ …

Genetic Architecture of Plasma Adiponectin Overlaps With the Genetics of Metabolic Syndrome–Related Traits

P Henneman, YS Aulchenko, RR Frants… - Diabetes …, 2010 - Am Diabetes Assoc
OBJECTIVE Adiponectin, a hormone secreted by adipose tissue, is of particular interest in
metabolic syndrome, because it is inversely correlated with obesity and insulin sensitivity …

Novel Locus FER Is Associated With Serum HMW Adiponectin Levels

L Qi, C Menzaghi, L Salvemini, C De Bonis… - Diabetes, 2011 - Am Diabetes Assoc
OBJECTIVE High molecular weight (HMW) adiponectin is a predominant isoform of
circulating adiponectin and has been related to type 2 diabetes. Previous linkage studies …

[HTML][HTML] Adiponectin SNP276 is associated with obesity, the metabolic syndrome, and diabetes in the elderly

WS Yang, YC Yang, CL Chen, IL Wu, JY Lu… - The American journal of …, 2007 - Elsevier
Background: Genetic variations of the human adiponectin gene are associated with
metabolic phenotypes, including obesity, insulin sensitivity, and diabetes. However, these …

Adiponectin Gene SNP276 Variants and Central Obesity Confer Risks for Hyperglycemia in Indigenous Taiwanese

MC Huang, TN Wang, KT Lee, YJ Wu… - … Journal of Medical …, 2010 - Wiley Online Library
This cross‐sectional study analyzed the effects of two single nucleotide polymorphisms
(SNP) of the adiponectin gene, SNP45 and SNP276, on hyperglycemia in indigenous …