The 3′-UTR of the adiponectin Q gene harbours susceptibility loci for atherosclerosis and its metabolic risk traits
N Muiya, M Al-Najai, AI Tahir, S Elhawari, D Gueco… - BMC medical …, 2013 - Springer
Background Adiponectin Q is a hormone that modulates several metabolic processes and
contributes to the suppression of biochemical pathways leading to metabolic syndrome …
contributes to the suppression of biochemical pathways leading to metabolic syndrome …
Genetic variants in ADIPOQ gene and the risk of type 2 diabetes: a case–control study of Chinese Han population
W Du, Q Li, Y Lu, X Yu, X Ye, Y Gao, J Ma, J Cheng… - Endocrine, 2011 - Springer
This study was to evaluate the association between ADIPOQ gene variants and type 2
diabetes mellitus (T2DM). TaqMan® assay was performed to test the genotypes in T2DM …
diabetes mellitus (T2DM). TaqMan® assay was performed to test the genotypes in T2DM …
Association of a polymorphic variant of the adiponectin gene with insulin resistance in african americans
C Specchia, K Scott, P Fortina… - Clinical and …, 2008 - Wiley Online Library
Hypertension, type 2 diabetes, and obesity are common complex disorders that contribute to
cardiovascular (CV) disease. Insulin resistance increases CV risk and is present in these …
cardiovascular (CV) disease. Insulin resistance increases CV risk and is present in these …
Meta-analysis of the association between adiponectin SNP 45, SNP 276, and type 2 diabetes mellitus
Y Dong, G Huang, X Wang, Z Chu, J Miao, H Zhou - PLoS One, 2020 - journals.plos.org
Objective The present study aimed to determine whether the polymorphisms at rs2241766
and rs1501299 on the ADIPOQ gene were related to the susceptibility of type 2 diabetes …
and rs1501299 on the ADIPOQ gene were related to the susceptibility of type 2 diabetes …
Functional characterization of promoter variants of the adiponectin gene complemented by epidemiological data
H Laumen, AD Saningong, IM Heid, J Hess… - Diabetes, 2009 - Am Diabetes Assoc
OBJECTIVE Adiponectin (APM1, ACDC) is an adipocyte-derived protein with downregulated
expression in obesity and insulin-resistant states. Several potentially regulatory single …
expression in obesity and insulin-resistant states. Several potentially regulatory single …
Genetic association of ADIPOQ gene variants with type 2 diabetes, obesity and serum adiponectin levels in south Indian population
K Ramya, KA Ayyappa, S Ghosh, V Mohan, V Radha - Gene, 2013 - Elsevier
Objective To investigate the genetic association of eight variants of the adiponectin gene
with type 2 diabetes mellitus (T2DM), obesity and serum adiponectin level in the south …
with type 2 diabetes mellitus (T2DM), obesity and serum adiponectin level in the south …
Common adiponectin gene variants show different effects on risk of cardiovascular disease and type 2 diabetes in European subjects
DR Gable, J Matin, R Whittall, H Cakmak… - Annals of human …, 2007 - Wiley Online Library
Alterations in the secretion of adipokines may explain the link between obesity, type 2
diabetes (T2DM) and coronary artery disease (CAD). These conditions have been …
diabetes (T2DM) and coronary artery disease (CAD). These conditions have been …
Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals
OBJECTIVE: Plasma adiponectin is strongly associated with various components of
metabolic syndrome, type 2 diabetes and cardiovascular outcomes. Concentrations are …
metabolic syndrome, type 2 diabetes and cardiovascular outcomes. Concentrations are …
Adiponectin gene variation associates with the increasing risk of type 2 diabetes in non-diabetic Japanese subjects
K Nakatani, K Noma, J Nishioka… - International …, 2005 - spandidos-publications.com
Adiponectin is an adipocyte-secreted protein that is known to modulate insulin sensitivity
and glucose homeostasis. A number of genetic variations have been studied. Among them …
and glucose homeostasis. A number of genetic variations have been studied. Among them …
Novel variations in the adiponectin gene (ADIPOQ) may affect distribution of oligomeric complexes
LC Kottyan, JG Woo, M Keddache, W Banach… - Springerplus, 2012 - Springer
Adiponectin is an obesity related protein that mediates the risk of type 2 diabetes in obese
individuals with its anti-inflammatory and insulin-sensitizing properties. To date, five …
individuals with its anti-inflammatory and insulin-sensitizing properties. To date, five …