Technological advances in DNA recovery and sequencing have drastically expanded the
scope of genetic analyses of ancient specimens to the extent that full genomic investigations …

Abstract The Gram-negative bacterium Yersinia pestis is the causative agent of the systemic
invasive infectious disease classically referred to as plague, and has been responsible for …

The first historically documented pandemic caused by Yersinia pestis began as the
Justinianic Plague in 541 within the Roman Empire and continued as the so-called First …

Although investigations of medieval plague victims have identified Yersinia pestis as the
putative etiologic agent of the pandemic, methodological limitations have prevented large …

The second plague pandemic, caused by Yersinia pestis, devastated Europe and the
nearby regions between the 14th and 18th centuries AD. Here we analyse human remains …

Plague is a pandemic human invasive disease caused by the bacterial agent Yersinia
pestis. We here report a comparison of 17 whole genomes of Y. pestis isolates from global …

The bacterial pathogen Yersinia pestis gave rise to devastating outbreaks throughout
human history, and ancient DNA evidence has shown it afflicted human populations as far …

From AD 1347 to AD 1353, the Black Death killed tens of millions of people in Europe,
leaving misery and devastation in its wake, with successive epidemics ravaging the …

Background Yersinia pestis has caused at least three human plague pandemics. The
second (Black Death, 14–17th centuries) and third (19–20th centuries) have been …

The bacteria Yersinia pestis is the etiological agent of plague and has caused human
pandemics with millions of deaths in historic times. How and when it originated remains …