Liver and kidney failure can lead to extensive accumulation of toxic metabolites in the blood
and tissues, such as bilirubin, blood ammonia, endotoxins, cytokines, creatinine, uric acid …

Hemoperfusion has emerged as an admirable adjuvant treatment for some severe diseases
and autoimmune diseases with favorable therapeutic effects because it can realize the …

Strong base anion exchange resin (eg, BL-300) is currently used to eliminate bilirubin from
blood in clinical hemoperfusion. However, there is a potential weakness of the resin to …

Biocompatible adsorbents play an essential role in hemoperfusion. Nevertheless, there are
no hemoperfusion adsorbents that can simultaneously remove small and medium toxins …

Resin hemoperfusion is a life-saving treatment for drug intoxication or hepatic failure of
patients. However, current resin adsorbents exhibit a limited hemocompatibility or low …

Purpose Extracorporeal blood purification systems based on combined
membrane/adsorption technologies are used in acute liver failure to replace detoxification …

Conventional absorbents for hemoperfusions suffer from low efficiency and slow absorption
with numerous side effects. In this research, we developed cellulose acetate (CA) …

Designing a hemoperfusion adsorbent for the excretion therapy of toxic heavy metals still
remains a great challenge due to the biosafety risks of non-biological materials and the …

Sepsis, a life-threatening and intractable disease without any specific treatment, is activated
by endotoxin. Some attempts at removing endotoxin to treat sepsis from the blood circulation …

Recently emerged hemoperfusion absorbents, eg ion-exchange resin, activated carbon, and
other porous materials, provide numerous novel possibilities to cure chronic liver failure …