[HTML][HTML] Ninjinyoeito ameliorated cigarette smoke extract-induced apoptosis and inflammation through JNK signaling inhibition in human lung fibroblasts

K Murata, N Fujita, R Takahashi - BMC Complementary Medicine and …, 2022 - Springer
Background Cigarette smoke is a major risk factor for various lung diseases, such as chronic
obstructive pulmonary disease (COPD). Ninjinyoeito (NYT), a traditional Chinese medicine …

Osthole, an ingredient from Cnidium monnieri, reduces the pyroptosis and apoptosis in bronchial epithelial cells

P Chen, Q Li, X Su, ZQ Zhang, GP Li - Journal of Asian Natural …, 2023 - Taylor & Francis
Osthole is the prominent active ingredient isolated from Cnidium. The role of osthole in
chronic obstructive pulmonary disease (COPD) was investigated herein. Bronchial epithelial …

Total tanshinones protect against acute lung injury through the PLCγ2/NLRP3 inflammasome signaling pathway

X Li, H Qiu, J Gan, Z Liu, S Yang, R Yuan… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Salvia miltiorrhiza Bunge is a widely used
traditional Chinese medicine with anticholinesterase, antitumor, and anti-inflammatory. Total …

Thymoquinone (Tq) protects necroptosis induced by autophagy/mitophagy‐dependent oxidative stress in human bronchial epithelial cells exposed to cigarette smoke …

AA Dera, M Al Fayi, H Otifi, M Alshyarba… - Journal of Food …, 2020 - Wiley Online Library
Chronic obstructive pulmonary disease (COPD) is characterized by cigarette smoke‐
induced emphysema. Herein, we demonstrate protective effects of Thymoquinone (Tq), an …

[HTML][HTML] YPL-001 shows various beneficial effects against cigarette smoke extract-induced emphysema formation: anti-inflammatory, anti-oxidative, and anti-apoptotic …

KH Lee, J Woo, J Kim, CH Lee, CG Yoo - Antioxidants, 2022 - mdpi.com
Inflammation, oxidative stress, and apoptosis are thought to be important causes of chronic
obstructive pulmonary disease (COPD). We investigated the effect of YPL-001 (under phase …

(−)-Epicatechin ameliorates cigarette smoke-induced lung inflammation via inhibiting ROS/NLRP3 inflammasome pathway in rats with COPD

X Tian, Y Xue, G Xie, Y Zhou, H Xiao, F Ding… - Toxicology and applied …, 2021 - Elsevier
Chronic obstructive pulmonary disease (COPD) with increased morbidity and mortality is a
worldwide healthcare challenge closely associated with cigarette smoking (CS). Currently …

N-acetylcysteine Attenuates Cigarette Smoke-induced Alveolar Epithelial Cell Apoptosis through Reactive Oxygen Species Depletion and Glutathione Replenish In …

J Zhao, M Han, Y Tian, P Zhao, X Liu… - Current …, 2024 - ingentaconnect.com
Background: Chronic obstructive pulmonary disease (COPD) is the third leading cause of
death worldwide. N-acetylcysteine (NAC) is well known for its antioxidant properties, along …

[HTML][HTML] Isoliquiritigenin inhibits cigarette smoke-induced COPD by attenuating inflammation and oxidative stress via the regulation of the Nrf2 and NF-κB signaling …

D Yu, X Liu, G Zhang, Z Ming, T Wang - Frontiers in pharmacology, 2018 - frontiersin.org
Chronic obstructive pulmonary disease (COPD) is the major leading cause of disease with
high-mortality worldwide. Cigarette smoke (CS) is a major factor for COPD. CS causes …

[HTML][HTML] So-Cheong-Ryoung-Tang attenuates pulmonary inflammation induced by cigarette smoke in bronchial epithelial cells and experimental mice

NR Shin, C Kim, CS Seo, JW Ko, YK Cho… - Frontiers in …, 2018 - frontiersin.org
So-Cheong-Ryoung-Tang is a traditionally used herbal formula for the treatment of
pulmonary diseases in China, Korea, and Japan. We investigated the protective effects of So …

Ameliorative effect of acetylshikonin on cigarette smoke-induced lung inflammation in mice

XY Zhang, YP Jia, Q Zhao, WY Wang… - Journal of Asian …, 2020 - Taylor & Francis
Cigarette smoke exposure is the major cause of chronic obstructive pulmonary disease
(COPD). Acetylshikonin was the active principle component of Purple Gromwell that show …