Parkinson's Disease Treatment and the Role of Genetic Polymorphisms in the Efficacy and Adverse Effects
H Usman, T Khalid, A Ghaffar - Precision Medicine Communications, 2021 - rootspress.org
Parkinson's disease (PD) is a relentlessly growing neurodegenerative disorder clinically
manifested by rigidity, tremors, and dyskinesia ascribed to loss of nigrostriatal dopaminergic …
manifested by rigidity, tremors, and dyskinesia ascribed to loss of nigrostriatal dopaminergic …
[HTML][HTML] Pharmacogenomics—a New Frontier for Individualized Treatment of Parkinson's Disease
JS Liu, Y Chen, DD Shi, BR Zhang… - Current …, 2023 - ncbi.nlm.nih.gov
Background Parkinson's disease (PD) is the second most common neurodegenerative
disease with a significant public health burden. It is characterized by the gradual …
disease with a significant public health burden. It is characterized by the gradual …
Pharmacological treatment and the prospect of pharmacogenetics in Parkinson's disease
K Kalinderi, L Fidani, Z Katsarou… - … journal of clinical …, 2011 - Wiley Online Library
Parkinson disease (PD) is a progressive movement disorder marked by tremor, rigidity,
bradykinesia and postural instability. Levodopa (l‐dopa), usually combined with a peripheral …
bradykinesia and postural instability. Levodopa (l‐dopa), usually combined with a peripheral …
The role of pharmacogenomics in the personalization of Parkinson's disease treatment
S Redenšek, V Dolžan - Pharmacogenomics, 2020 - Future Medicine
Parkinson's disease (PD)-related phenotypes can vary among patients substantially,
including response to dopaminergic treatment in terms of efficacy and occurrence of adverse …
including response to dopaminergic treatment in terms of efficacy and occurrence of adverse …
Effects of genetic variability in dopaminergic pathway on treatment response in Parkinson's disease
S Redenšek, M Trošt, V Dolžan - Parkinson's Disease, ed …, 2018 - books.google.com
Parkinson's disease (PD) is a chronic progressive neurodegenerative brain disorder
presenting with motor signs and symptoms, such as akinesia, rest tremor, rigidity, and later …
presenting with motor signs and symptoms, such as akinesia, rest tremor, rigidity, and later …
How close are we to individualized medicine for Parkinson's disease?
HJ Kim, B Jeon - Expert Review of Neurotherapeutics, 2016 - Taylor & Francis
Introduction: There is a considerable inter-individual heterogeneity in clinical features,
disease course, and treatment response in Parkinson's disease (PD), which can be …
disease course, and treatment response in Parkinson's disease (PD), which can be …
Polymorphism in candidate genes: implications for the risk and treatment of idiopathic Parkinson's disease
Y Gilgun-Sherki, R Djaldetti, E Melamed… - The pharmacogenomics …, 2004 - nature.com
Idiopathic Parkinson's disease (IPD) is a progressive neurodegenerative disorder for which
no restorative or neuroprotective therapy is available. Interest has recently been directed to …
no restorative or neuroprotective therapy is available. Interest has recently been directed to …
Pharmacogenetics and levodopa induced motor complications
K Kalinderi, V Papaliagkas, L Fidani - International Journal of …, 2019 - Taylor & Francis
Aim: L-dopa remains the most effective symptomatic therapy for Parkinson's disease (PD)
but unfortunately, its chronic use is often associated with motor complications. This review …
but unfortunately, its chronic use is often associated with motor complications. This review …
An update on the pharmacogenetic considerations when prescribing dopamine receptor agonists for Parkinson's disease
P Ayuso, FJ Jiménez-Jiménez… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Parkinson's disease is a chronic neurodegenerative multisystemic disorder that
affects approximately 2% of the population over 65 years old. This disorder is characterized …
affects approximately 2% of the population over 65 years old. This disorder is characterized …
Pharmacogenetics of drug response in Parkinson's disease
E Džoljić, I Novaković, M Krajinovic… - International Journal …, 2015 - Taylor & Francis
Parkinson's disease (PD) is a debilitating, demoralizing and financially devastating condition
affecting 1% of population at the age of 60 years. Thus, very important issue to address is …
affecting 1% of population at the age of 60 years. Thus, very important issue to address is …