The efficacy of the N-methyl-D-aspartate receptor antagonist ketamine as an analgesic
agent is still under debate, especially for indications such as chronic pain. To understand the …

Objectives This study had five objectives: 1) to measure and compare total opioid use and
number of opioid doses in patients treated with opioids versus ketamine in conjunction with …

Ketamine has diverse effects that may be of relevance to chronic pain including: N-methyl-d-
aspartic acid, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid, kainate, γ …

The analgesic effect of ketamine is primarily based on the antagonism of the N-methyl-d-
aspartate (NMDA) receptor. Activation of NMDA receptors may play a crucial role in the …

Background There is no recommendation in Europe for the use of ketamine in patients with
chronic pain. The heterogeneity of practice highlights the need to seek the advice of experts …

After nearly half a century on the market, ketamine still occupies a unique corner in the
medical armamentarium of anesthesiologists or clinicians treating pain. Over the last two …

Background: Pain is a common presenting complaint and there is considerable debate
regarding the best practice for analgesia in the pre‐hospital environment for trauma patients …

Objective There has been increased interest in the use of low‐dose ketamine (LDK) as an
alternative analgesic for the management of acute pain in the emergency department (ED) …

Background Ketamine is often used for the management of refractory chronic pain. There is,
however, a paucity of trials exploring its analgesic effect several weeks after intravenous …

ObjectivesThe aim of the study is to determine the performance of low-dose ketamine (LDK)
as an analgesic for acute pain management in adult patients in the emergency department …