Ketamine is an injectable anesthetic induction agent that has been reported to have
analgesic activity in pain from a variety of mechanisms, but predominantly in neuralgic and …

There is a need for alternative non-opioid analgesics for the treatment of acute, chronic, and
refractory pain in the emergency department (ED). Ketamine is a fast acting N-methyl-d …

Objective: To evaluate the evidence for the use of intravenous ketamine for analgosedation
in the intensive care unit. Methods: MEDLINE and EMBASE were queried from inception …

OBJECTIVE: We assessed the analgesic effect and feasibility of low-dose ketamine
combined with a reduced dose of hydromorphone for emergency department (ED) patients …

BACKGROUND: We describe our experience of utilizing sub-dissociative dose ketamine
(SDK) in managing a variety of acute and chronic painful conditions in the emergency …

The benefits of ketamine in reducing pain are largely based on case reports and small
clinical trials. We present a case series describing the application and efficacy of …

BACKGROUND Intravenous ketamine is commonly used for pain management in the
civilian prehospital setting. Several studies have evaluated its effectiveness in the military …

For ketamine's fiftieth birthday, a narrative review of this unique drug in pain management is
presented. Its history is traced from its conception, and its heritage, as a phencyclidine …

Ketamine was first synthesized in 1962, patented in Belgium in 1963, and approved for
human use by the US Food and Drug Administration in 1970. Unlike inhalation anaesthetics …

In humans, proof of long-term efficacy of ketamine treatment in neuropathic pain is lacking.
To improve our understanding of ketamine behavior under various administration …