The present meta-analysis is performed to determine the association of C1236T and
C3435T polymorphisms in the MDR1 gene. Google Scholar, PubMed, and Science Direct …

Infertility is a common problem affecting one in six couples, and in 30% of infertile couples,
the male factor is a major cause due to defective sperm quality. P-glycoprotein (P-gp), a …

Background: Number of studies have been performed to investigate the relationship
between the CYP1A1 rs4646903 polymorphism and male infertility risk, but the sample size …

Polymorphisms in multidrug resistance (MDR1) gene play an important role in influencing
the pharmacological action and toxicity profile of a large number of therapeutic agents, and …

Background Epidemiological studies have evaluated the association between 3801T> C
polymorphism of CYP1A1 gene and the risk for idiopathic male infertility, but the results are …

BACKGROUND: The CYP1A1 gene is a polymorphic gene and encodes for the CYP1A1
enzyme that catalyzes the bioactivation of polycyclic aromatic hydrocarbons (PAHs). PAHs …

BACKGROUND: It is acknowledged that Cytochrome P450 1B1 (CYP1B1) plays a crucial
role in metabolism and is involved in lots of diseases. We carried out this study to evaluate …

Enzymes belonging to the glutathione-S-transferase (GST) and cytochrome P450 (CYP)
families are involved in a 2-stage detoxification process of a wide range of environmental …

Studies of the relationship between male infertility and CYP1A1 polymorphisms are
inconclusive. To drive a more precise estimation, we performed a meta-analysis based on …

Prostate cancer is one of the most common malignancies in men. The multidrug resistance 1
gene (MDR1) is an important candidate gene for prostate cancer. The aim of this study was …