[HTML][HTML] The role of RNA splicing factors in cancer: regulation of viral and human gene expression in human papillomavirus-related cervical cancer

A Cerasuolo, L Buonaguro, FM Buonaguro… - Frontiers in cell and …, 2020 - frontiersin.org
The spliceosomal complex components, together with the heterogeneous nuclear
ribonucleoproteins (hnRNPs) and serine/arginine-rich (SR) proteins, regulate the process of …

[HTML][HTML] Control of human papillomavirus gene expression by alternative splicing

SV Graham, AAA Faizo - Virus research, 2017 - Elsevier
Human papillomaviruses possess circular double stranded DNA genomes of around 8 kb in
size from which multiple mRNAs are synthesized during an infectious life cycle. Although at …

Human papillomavirus 16 oncoprotein expression is controlled by the cellular splicing factor SRSF2 (SC35)

M McFarlane, AI MacDonald, A Stevenson… - Journal of …, 2015 - Am Soc Microbiol
High-risk human papillomaviruses (HR-HPV) cause anogenital cancers, including cervical
cancer, and head and neck cancers. Human papillomavirus 16 (HPV16) is the most …

[HTML][HTML] The alternative splicing factor hnRNP A1 is up-regulated during virus-infected epithelial cell differentiation and binds the human papillomavirus type 16 late …

T Cheunim, J Zhang, SG Milligan, MG McPhillips… - Virus research, 2008 - Elsevier
Human papillomavirus type 16 (HPV16) infects anogenital epithelia and is the etiological
agent of cervical cancer. We showed previously that HPV16 infection regulates the key …

Human papillomavirus regulation of SR proteins

M McFarlane, SV Graham - Biochemical Society Transactions, 2010 - portlandpress.com
Splicing is a cellular process essential for mRNA biogenesis. There are two types of splicing:
constitutive and alternative splicing. During constitutive splicing, non-coding intron …

RNPS1 functions as an oncogenic splicing factor in cervical cancer cells

B Deka, P Chandra, P Yadav, A Rehman, S Kumari… - IUBMB …, 2023 - Wiley Online Library
Numerous recent studies suggest that cancer‐specific splicing alteration is a critical
contributor to the pathogenesis of cancer. RNA‐binding protein with serine‐rich domain 1 …

RNA splicing factors regulated by HPV16 during cervical tumour progression

S Mole, M McFarlane, T Chuen‐Im… - The Journal of …, 2009 - Wiley Online Library
The most prevalent human papillomaviruses (HPVs) causing cervical disease are the 'high‐
risk'HPV types 16 and 18. All papillomaviruses express a transcription factor, E2, that can …

Competing endogenous RNA (ceRNA) networks and splicing switches in cervical cancer: HPV oncogenesis, clinical significance and therapeutic opportunities

A Basera, R Hull, D Demetriou, DO Bates… - Microorganisms, 2022 - mdpi.com
Cervical cancer (CC) is the primary cause of female cancer fatalities in low-middle-income
countries (LMICs). Persistent infections from the human papillomavirus (HPV) can result in …

SF2/ASF binds the human papillomavirus type 16 late RNA control element and is regulated during differentiation of virus-infected epithelial cells

MG McPhillips, T Veerapraditsin, SA Cumming… - Journal of …, 2004 - Am Soc Microbiol
Pre-mRNA splicing occurs in the spliceosome, which is composed of small
ribonucleoprotein particles (snRNPs) and many non-snRNP components. SR proteins, so …

Serine/arginine-rich splicing factor 3 and heterogeneous nuclear ribonucleoprotein A1 regulate alternative RNA splicing and gene expression of human …

M Ajiro, S Tang, J Doorbar, ZM Zheng - Journal of virology, 2016 - Am Soc Microbiol
ABSTRACT Human papillomavirus 18 (HPV18) is the second most common oncogenic HPV
type associated with cervical, anogenital, and oropharyngeal cancers. Like other oncogenic …