For patients with EPL, is the addition of mifepristone to vaginal misoprostol more effective than medication management with misoprostol alone?

J Flament, C Thomson, K Nierenberg - Evidence-Based Practice, 2021 - journals.lww.com
For patients with first trimester early pregnancy loss, pretreatment with mifepristone before
misoprostol increases treatment success more than vaginal misoprostol alone, with a …

Management of early pregnancy loss with mifepristone and misoprostol: clinical predictors of success from a randomized trial

S Sonalkar, NC Koelper, MD Creinin, JM Atrio… - Fertility and …, 2019 - fertstert.org
Objective To evaluate characteristics associated with treatment success in women receiving
medical management for early pregnancy loss (EPL). Design We performed a secondary …

Mifepristone followed by misoprostol compared with placebo followed by misoprostol as medical treatment for early pregnancy loss (the Triple M trial): A double-blind …

C Hamel, S Coppus, J van den Berg, E Hink… - …, 2021 - thelancet.com
Background Worldwide, millions of women seek treatment for early pregnancy loss (EPL)
annually. Medical management with misoprostol is widely used, but only effective 60% of the …

Mifepristone Followed by Misoprostol Compared with Placebo Followed by Misoprostol as Medical Treatment for Early Pregnancy Loss (the Triple M trial): A Double …

C HAMEL, S COPPUS, J VAN DEN BERG… - Fertility & …, 2022 - World Scientific
Background: Worldwide, millions of women seek treatment for early pregnancy loss (EPL)
annually. Medical management with misoprostol is widely used, but only effective 60% of the …

Early pregnancy loss

LK Perriera, BA Chen, AM Gariepy - Obstetric Evidence Based …, 2022 - taylorfrancis.com
There are several additional studies looking at mifepristone followed by vaginal or oral
misoprostol. There is now clear evidence that mifepristone combined with misoprostol …

Management of early pregnancy loss with mifepristone and misoprostol: clinical predictors of treatment success from a randomized trial

S Sonalkar, N Koelper, MD Creinin, JM Atrio… - American journal of …, 2020 - Elsevier
Background Early pregnancy loss is a common event in the first trimester, occurring in 15%–
20% of confirmed pregnancies. A common evidence-based medical regimen for early …

Economic evaluation of a randomized controlled trial comparing mifepristone and misoprostol with misoprostol alone in the treatment of early pregnancy loss

CC Hamel, MPLM Snijders, SFPJ Coppus… - Plos one, 2022 - journals.plos.org
Background In case of early pregnancy loss (EPL) women can either choose for expectant,
medical or surgical management. One week of expectant management is known to lead to …

Misoprostol treatment for early pregnancy loss: an international survey

Y Mizrachi, G Shoham, M Leong, R Sagiv… - Reproductive …, 2021 - Elsevier
Research question What is the global variability in misoprostol treatment for the
management of early pregnancy loss (EPL)? Design An international web-based survey of …

The Success of Mifepristone and Misoprostol in the Management of Early Pregnancy Loss at a Community Hospital: A Prospective Study

S Farooqi, E Lackie, A Pham, L Zolis, K Sharma… - Journal of Obstetrics and …, 2024 - Elsevier
Background This prospective single-arm study was conducted to understand the expulsion
rate of the gestational sac in the management of early pregnancy loss (EPL). Methods We …

[HTML][HTML] Sequential use of mifepristone and misoprostol in treatment of early pregnancy failure appears more effective than misoprostol alone: a retrospective study

J van den Berg, JM van den Bent, MP Snijders… - European Journal of …, 2014 - Elsevier
Objective Is treatment of early pregnancy failure (EPF) with sequential use of mifepristone
and misoprostol more effective than treatment with misoprostol alone? Study design In a …