Cutaneous dysbiosis may amplify barrier dysfunction in patients with atopic dermatitis

M Hammond, A Gamal, PK Mukherjee… - Frontiers in …, 2022 - frontiersin.org
Atopic dermatitis (AD) is associated with cutaneous dysbiosis, barrier defects, and immune
dysregulation, but the interplay between these factors needs further study. Early-onset …

Atopic dermatitis microbiomes stratify into ecologic dermotypes enabling microbial virulence and disease severity

ASL Tay, C Li, T Nandi, KR Chng, AK Andiappan… - Journal of Allergy and …, 2021 - Elsevier
Background Atopic dermatitis (AD) is a common skin disease affecting up to 20% of the
global population, with significant clinical heterogeneity and limited information about …

Skin dysbiosis in the microbiome in atopic dermatitis is site-specific and involves bacteria, fungus and virus

RD Bjerre, JB Holm, A Palleja, J Sølberg, L Skov… - BMC microbiology, 2021 - Springer
Background Microbial dysbiosis with increased Staphylococcus aureus (S. aureus)
colonization on the skin is a hallmark of atopic dermatitis (AD), however most microbiome …

The influence of microbiome dysbiosis and bacterial biofilms on epidermal barrier function in atopic dermatitis—an update

L Blicharz, L Rudnicka, J Czuwara… - International Journal of …, 2021 - mdpi.com
Atopic dermatitis (AD) is a common inflammatory dermatosis affecting up to 30% of children
and 10% of adults worldwide. AD is primarily driven by an epidermal barrier defect which …

Microbial and transcriptional differences elucidate atopic dermatitis heterogeneity across skin sites

N Ottman, M Barrientos‐Somarribas, N Fyhrquist… - Allergy, 2021 - Wiley Online Library
It is well established that different sites in healthy human skin are colonized by distinct
microbial communities due to different physiological conditions. However, few studies have …

Relations between epidermal barrier dysregulation and Staphylococcus species–dominated microbiome dysbiosis in patients with atopic dermatitis

C Altunbulakli, M Reiger, AU Neumann… - Journal of Allergy and …, 2018 - jacionline.org
LETTERS TO THE EDITOR 1643 such as the skin microbiota, have been described as risk
factors for AD. 3, 4 Reduction of microbiome diversity, accompanied by an increase in …

Microbiome in atopic dermatitis

U Wollina - Clinical, Cosmetic and Investigational Dermatology, 2017 - Taylor & Francis
Atopic dermatitis (AD) is a common chronic inflammatory skin disease affecting~ 10–20% of
the general population. AD is characterized by disturbances in epidermal barrier function …

Association between barrier impairment and skin microbiota in atopic dermatitis from a global perspective: unmet needs and open questions

R Darlenski, AL Kozyrskyj, JW Fluhr… - Journal of Allergy and …, 2021 - Elsevier
Atopic diathesis encompassing atopic dermatitis (AD), allergic rhinoconjunctivitis, food
allergy, eosinophilic esophagitis, and asthma is a widely prevalent condition with a broad …

Adding Fuel to the Fire? The Skin Microbiome in Atopic Dermatitis

SS Kashaf, HH Kong - Journal of Investigative Dermatology, 2024 - Elsevier
Atopic dermatitis (AD) is a multifactorial, heterogeneous disease characterized by epidermal
barrier dysfunction, immune system dysregulation, and skin microbiome alterations. Skin …

The skin microbiome of patients with atopic dermatitis normalizes gradually during treatment

VD Khadka, FM Key, C Romo-González… - Frontiers in Cellular …, 2021 - frontiersin.org
Background Atopic dermatitis (AD) is characterized by an altered skin microbiome
dominantly colonized by S. aureus. Standard treatment includes emollients, anti …