The skin microbiome in the first year of life and its association with atopic dermatitis

A Rapin, EM Rehbinder, M Macowan, C Pattaroni… - Allergy, 2023 - Wiley Online Library
Background Early‐life microbial colonization of the skin may modulate the immune system
and impact the development of atopic dermatitis (AD) and allergic diseases later in life. To …

Distinct skin microbiota imbalance and responses to clinical treatment in children with atopic dermatitis

Y Liu, S Wang, W Dai, Y Liang, C Shen, Y Li… - Frontiers in cellular …, 2020 - frontiersin.org
Background: Atopic dermatitis (AD) is a common cutaneous disease, associated with
imbalances in the skin microbiota. Objective: To explore the characteristics of the cutaneous …

Effects of the Staphylococcus aureus and Staphylococcus epidermidis Secretomes Isolated from the Skin Microbiota of Atopic Children on CD4+ T Cell Activation

E Laborel-Préneron, P Bianchi, F Boralevi, P Lehours… - PLoS …, 2015 - journals.plos.org
Interactions between the immune system and skin bacteria are of major importance in the
pathophysiology of atopic dermatitis (AD), yet our understanding of them is limited. From a …

Staphylococcal communities on skin are associated with atopic dermatitis and disease severity

SM Edslev, CM Olesen, LB Nørreslet, AC Ingham… - Microorganisms, 2021 - mdpi.com
The skin microbiota of atopic dermatitis (AD) patients is characterized by increased
Staphylococcus aureus colonization, which exacerbates disease symptoms and has been …

Evolving approaches to profiling the microbiome in skin disease

Y Chen, R Knight, RL Gallo - Frontiers in Immunology, 2023 - frontiersin.org
Despite its harsh and dry environment, human skin is home to diverse microbes, including
bacteria, fungi, viruses, and microscopic mites. These microbes form communities that may …

The immunological and structural epidermal barrier dysfunction and skin microbiome in atopic dermatitis-an update

T Çetinarslan, L Kümper… - Frontiers in Molecular …, 2023 - frontiersin.org
Atopic dermatitis (AD) is a common, chronic and relapsing inflammatory skin disease with
various clinical presentations and combinations of symptoms. The pathophysiology of AD is …

Skin microbiome and its association with host cofactors in determining atopic dermatitis severity

L Rauer, M Reiger, M Bhattacharyya… - Journal of the …, 2023 - Wiley Online Library
Background Atopic dermatitis (AD) is a heterogeneous, chronic inflammatory skin disease
linked to skin microbiome dysbiosis with reduced bacterial diversity and elevated relative …

[HTML][HTML] Transplantation of human skin microbiota in models of atopic dermatitis

IA Myles, KW Williams, JD Reckhow, ML Jammeh… - JCI insight, 2016 - ncbi.nlm.nih.gov
Atopic dermatitis (AD) is characterized by reduced barrier function, reduced innate immune
activation, and susceptibility to Staphylococcus aureus. Host susceptibility factors are …

Mechanisms of microbe-immune system dialogue within the skin

N Lunjani, S Ahearn-Ford, FS Dube, C Hlela… - Genes & …, 2021 - nature.com
The prevalence and severity of dermatological conditions such as atopic dermatitis have
increased dramatically during recent decades. Many of the factors associated with an …

Epithelial barrier dysfunctions in atopic dermatitis: a skin–gut–lung model linking microbiome alteration and immune dysregulation

TH Zhu, TR Zhu, KA Tran… - British Journal of …, 2018 - academic.oup.com
Background Atopic dermatitis is a systemic disorder characterized by abnormal barrier
function across multiple organ sites. Causes of epidermal barrier breakdown are complex …