Lung toxicity is a rare but serious side effect of sirolimus, a mammalian target of rapamycin
inhibitor used as an immunosuppressive agent in solid-organ transplant recipients. We …

Background. Pulmonary toxicity has recently been recognized as a potentially serious
complication associated with sirolimus therapy. We further detail this condition on the basis …

INTRODUCTION: An important side effect of sirolimus, a drug often used in organ
transplantation, is pulmonary toxicity. MATERIALS AND METHODS: We present five kidney …

Sirolimus is a well-known, potent immunosuppressant that is widely used in solid-organ
transplantation, but it is not without potential side effects. A rare but devastating adverse …

Introduction: Since its approval in 1999 for immunosuppression in kidney transplantation,
sirolimus has gained popularity for its ability to provide immunosuppression without the …

Sirolimus is a potent immunosuppressive agent used with increasing frequency in solid
organ transplantation (SOT). However, it has been associated with rare but devastating …

CONCLUSION: With the more common use of sirolimus in transplant patients physicians
must be aware of the possibility of lung toxicity related to this drug. The diagnosis can be a …

Methods: A retrospective review of all patients treated with sirolimus in our center is done.
Medical records from 2 liver transplant recipients with suspected sirolimus-associated …

The differential diagnosis of pulmonary infiltrates after solid-organ transplantation presents a
broad differential diagnosis including opportunistic infections and drug-induced lung …

Sirolimus is a potent immunosuppressive drug that began to be used in the last few years.
This drug was initially used in renal transplantation but its use in other solid organ …