A Label‐Free Multitechnique Approach to Characterize the Interaction of Bioactive Compounds with Biomimetic Interfaces

E Fernandes, RR Costa, R Machado, RL Reis… - Small …, 2024 - Wiley Online Library
Extensive research has been conducted on biomimetic interfaces mimicking the complex
and diverse microenvironment of cell membranes to gain insights into bioactive compound …

[HTML][HTML] Supported lipid bilayers and the study of two-dimensional binding kinetics

T Dam, M Chouliara, V Junghans… - Frontiers in molecular …, 2022 - frontiersin.org
Binding between protein molecules on contacting cells is essential in initiating and
regulating several key biological processes. In contrast to interactions between molecules in …

Mimicking the mammalian plasma membrane: An overview of lipid membrane models for biophysical studies

A Luchini, G Vitiello - Biomimetics, 2020 - mdpi.com
Cell membranes are very complex biological systems including a large variety of lipids and
proteins. Therefore, they are difficult to extract and directly investigate with biophysical …

Permeability of drugs and hormones through a lipid bilayer: insights from dual-resolution molecular dynamics

M Orsi, JW Essex - Soft Matter, 2010 - pubs.rsc.org
The unassisted permeation process of β-blocker drugs (alprenolol, atenolol, pindolol) and
steroid hormones (progesterone, testosterone) through a lipid membrane is simulated by a …

Fluid interfaces as models for the study of lipid-based films with biophysical relevance

PG Argudo, A Maestro, E Guzmán - Coatings, 2023 - mdpi.com
This comprehensive review aims to provide a deep insight into the fascinating field of
biophysics in living organisms through the study of model fluid interfaces that mimic specific …

Membrane interactions in drug delivery: Model cell membranes and orthogonal techniques

AI Bunea, S Harloff-Helleberg, R Taboryski… - Advances in colloid and …, 2020 - Elsevier
To generate the desired effect in the human body, the active pharmaceutical ingredient
usually needs to interact with a receptor located on the cell membrane or inside the cell …

Molecular interaction of natural compounds with lipid bilayer membranes: Towards a better understanding of their biological and pharmaceutical actions

G Fabre - 2015 - theses.fr
One of the key lockers to understand mechanisms of biological action of drugs and natural
compounds is their capacity to incorporate/cross lipid bilayer membranes. In the light of …

[HTML][HTML] Real-time analysis of protein and protein mixture interaction with lipid bilayers

S Heider, E Reimhult, C Metzner - Biochimica et Biophysica Acta (BBA) …, 2018 - Elsevier
Artificial lipid bilayers in the form of planar supported or vesicular bilayers are commonly
used as models for studying interaction of biological membranes with different substances …

Design and use of model membranes to study biomolecular interactions using complementary surface-sensitive techniques

LA Clifton, RA Campbell, F Sebastiani… - Advances in colloid and …, 2020 - Elsevier
Cellular membranes are complex structures and simplified analogues in the form of model
membranes or biomembranes are used as platforms to understand fundamental properties …

[HTML][HTML] Surface interactions determined by stereostructure on the example of 7-hydroxycholesterol epimers–the Langmuir monolayer study

A Chachaj-Brekiesz, A Wnętrzak, E Lipiec… - … et Biophysica Acta (BBA …, 2019 - Elsevier
Stereoselective interactions are pivotal for molecular recognition between biomolecules and
lipid surfaces. The aim of this study was to determine factors differencing molecular …