Dysfunction of programmed embryo senescence is linked to genetic developmental defects
C De Lope, R García-Lucena, M Magariños… - …, 2023 - journals.biologists.com
Developmental senescence is a form of programmed senescence that contributes to
morphogenesis during embryonic development. We showed recently that the SIX1 …
morphogenesis during embryonic development. We showed recently that the SIX1 …
The benefits of aging: cellular senescence in normal development
A Pérez‐Garijo, H Steller - The EMBO Journal, 2014 - embopress.org
Senescence is a form of cellular aging that limits the proliferative capacity of cells.
Senescence can be triggered by different stress stimuli, such as DNA damage or oncogene …
Senescence can be triggered by different stress stimuli, such as DNA damage or oncogene …
A role for cellular senescence in birth timing
JM Cha, DM Aronoff - Cell Cycle, 2017 - Taylor & Francis
Senescence contributes to the local and systemic aging of tissues and has been associated
with age-related diseases. Recently, roles for this process during pregnancy have come to …
with age-related diseases. Recently, roles for this process during pregnancy have come to …
Developing senescence to remodel the embryo
Cellular senescence is an irreversible form of cell cycle arrest that has been linked to
several pathological conditions. In particular, senescence can function as a tumor …
several pathological conditions. In particular, senescence can function as a tumor …
[HTML][HTML] Apoptosis during embryonic tissue remodeling is accompanied by cell senescence
CI Lorda-Diez, B Garcia-Riart, JA Montero… - Aging (Albany …, 2015 - ncbi.nlm.nih.gov
This study re-examined the dying process in the interdigital tissue during the formation of
free digits in the developing limbs. We demonstrated that the interdigital dying process was …
free digits in the developing limbs. We demonstrated that the interdigital dying process was …
Cellular senescence and developmental defects
A Klein, M Rhinn, WM Keyes - The FEBS Journal, 2023 - Wiley Online Library
Cellular senescence is a distinct state that is frequently induced in response to ageing and
stress. Yet studies have also uncovered beneficial functions in development, repair and …
stress. Yet studies have also uncovered beneficial functions in development, repair and …
[HTML][HTML] Programmed cell senescence during mammalian embryonic development
D Muñoz-Espín, M Cañamero, A Maraver… - Cell, 2013 - cell.com
Cellular senescence disables proliferation in damaged cells, and it is relevant for cancer
and aging. Here, we show that senescence occurs during mammalian embryonic …
and aging. Here, we show that senescence occurs during mammalian embryonic …
Cellular senescence in development, regeneration and disease
M Rhinn, B Ritschka, WM Keyes - Development, 2019 - journals.biologists.com
Cellular senescence is a state comprising an essentially irreversible proliferative arrest
combined with phenotypic changes and pronounced secretory activity. Although …
combined with phenotypic changes and pronounced secretory activity. Although …
[HTML][HTML] Senescence and Apoptosis During in vitro Embryo Development in a Bovine Model
P Ramos-Ibeas, I Gimeno, K Cañón-Beltrán… - Frontiers in cell and …, 2020 - frontiersin.org
According to the World Health Organization, infertility affects up to 14% of couples under
reproductive age, leading to an exponential rise in the use of assisted reproduction as a …
reproductive age, leading to an exponential rise in the use of assisted reproduction as a …
Conserved and novel functions of programmed cellular senescence during vertebrate development
H Davaapil, JP Brockes, MH Yun - Development, 2017 - journals.biologists.com
Cellular senescence, a form of stable cell cycle arrest that is traditionally associated with
tumour suppression, has been recently found to occur during mammalian development …
tumour suppression, has been recently found to occur during mammalian development …