Regenerative medicine is an emerging therapeutic method that aims to reconstruct tissues
and organs. This advanced therapeutic approach has demonstrated great potential in …

Perianal fistulae are common in Crohn's disease but rarely heal without treatment. The main
aim of treatment is to effectively close the fistula without affecting sphincter integrity and …

A fistula is defined as an abnormal communication between two epithelium-lined surfaces,
and fistula-in-ano consists of an abnormal tract connecting the anal canal or rectum with the …

See “Long-term safety and efficacy of local microinjection combining autologous microfat
and adipose-derived stromal vascular fraction for the treatment of refractory perianal fistula …

Perianal fistulae in patients with Crohn's disease (CD) can be associated with significant
morbidity resulting in negative impact on quality of life. The last two decades have seen …

Background: The management of complex perianal fistulas in Crohn's disease (CD)
represents a challenge for patients, gastroenterologists and colorectal surgeons. There are …

Perianal fistula in patients with Crohn's disease is an extremely challenging condition. The
disease tends to reoccur, and with current treatment options, a large number of patients are …

Fistulae represent an important complication of Crohn's disease (CD), affecting more than
50% of CD patients. 1–3 The majority of fistulae in CD occur in the perianal area, and the …

Background Perianal fistulas (PF) affect one-third patients with Crohn's disease (CD) with
limited therapeutic options. There is dearth of literature on safety and efficacy of bone …

BACKGROUND: Refractory perianal Crohn's disease remains notoriously difficult to treat.
We developed a novel technology using a commercially available bioabsorbable fistula plug …