Dendritic cells (DC) are professional antigen-presenting cells whose primary function is the
initiation of immune response. Based on the finding that the immune system usually fails to …

Therapeutic vaccines that treat cancers with the help of the patient's own immune system
signify a feasible option for active immunotherapy against the disease. Dendritic cells (DCs) …

Antigen presentation is a critical regulatory element for the induction of cellular immune
responses. Thus, one of the principal current goals of tumor immunotherapy is to control and …

For several decades, approaches utilizing nonspecific immune stimulants have provided
evidence that the immune system, when properly activated, may eradicate cancer cells …

The discovery that dendritic cells (DC) play a key role in regulating antitumor immunity has
prompted considerable efforts in developing DC-based cancer vaccines for use in clinical …

The immunogenicity of tumors has been established. Aspecific stimulation of immunity, such
as by cytokine therapy, has been shown to induce durable clinical remissions in metastatic …

Dendritic cells (DCs) are believed to be the most potent antigen-presenting cells able to link
the innate and adaptive immune systems. Many studies have focused on different …

Dendritic cell (DC) vaccination in cancer patients aims to induce or augment an effective
antitumor immune response against tumor antigens and was first explored in a clinical trial …

Dendritic cells (DCs) are the most powerful professional antigen-presenting cells and are
unique in their capability to initiate, maintain and regulate the intensity of primary immune …

The characterization of tumorassociated antigens recognized by human T lymphocytes in a
major histocompatibility complex (MHC) restricted fashion has opened new possibilities for …