Recent Advances in Antitumor Dendritic Cell Vaccines

C Ge, X Yang, J Xin, X Gong, X Wang… - Cancer Biotherapy & …, 2023 - liebertpub.com
Background: Dendritic cells (DCs) are the most important antigen-presenting cells in the
body and play a key role in antigen recognition, uptake, processing, and presentation and …

A review of dendritic cell therapy for cancer: progress and challenges

GM Mantia-Smaldone, CS Chu - BioDrugs, 2013 - Springer
Dendritic cells are the professional antigen-presenting cells of the innate immune system
with the potential to generate robust antigen-specific T cell immune responses …

Exploiting dendritic cells in the development of cancer vaccines

L Bracci, I Capone, F Moschella, E Proietti… - Expert review of …, 2013 - Taylor & Francis
Due to their central role in priming and modulating the immune response, dendritic cells
(DCs) represent an ideal instrument for the design of effective immunotherapeutic strategies …

Dendritic cell-based immunotherapy

T Osada, TM Clay, CY Woo, MA Morse… - International reviews of …, 2006 - Taylor & Francis
Dendritic cells (DCs) play a crucial role in the induction of antigen-specific T-cell responses,
and therefore their use for the active immunotherapy of malignancies has been studied with …

Naturally circulating dendritic cells to vaccinate cancer patients

KF Bol, J Tel, IJM De Vries, CG Figdor - Oncoimmunology, 2013 - Taylor & Francis
Dendritic cell-based immunotherapy is a promising strategy against cancer that appears to
be feasible, safe and to induce potent tumor-specific immune responses. The use of …

Dendritic cell-based vaccines against cancer: challenges, advances and future opportunities

C Fu, T Ma, L Zhou, QS Mi, A Jiang - Immunological investigations, 2022 - Taylor & Francis
As the most potent professional antigen presenting cells, dendritic cells (DCs) have the
ability to activate both naive CD4 and CD8 T cells. Recognized for their exceptional ability to …

Cellular immunotherapy with dendritic cells in cancer: current status

A Nencioni, P Brossart - Stem Cells, 2004 - academic.oup.com
Dendritic cells (DCs) are specialized antigen‐presenting cells whose immunogenicity leads
to the induction of antigen‐specific immune responses. DCs can easily be generated ex vivo …

Experimental vaccine strategies for cancer immunotherapy

CH Chen, TC Wu - Journal of biomedical science, 1998 - karger.com
Recently, cancer immunotherapy has emerged as a therapeutic option for the management
of cancer patients. This is based on the fact that our immune system, once activated, is …

Current methods for loading dendritic cells with tumor antigen for the induction of antitumor immunity

Y Zhou, ML Bosch, ML Salgaller - Journal of immunotherapy, 2002 - journals.lww.com
The immunotherapy of cancer is predicated on the belief that it is possible to generate a
clinically meaningful antitumor response that provides patient benefit, such as improvement …

Dendritic cell therapy in cancer treatment; the state-of-the-art

M Sadeghzadeh, S Bornehdeli… - Life sciences, 2020 - Elsevier
Dendritic cells (DCs) are considered as professional antigen presenting cells (APCs),
containing a variety of subsets, that can be resident in organs or migrating among the …