Mechanisms of action of dendritic cell vaccines for the treatment of cancer

C Zhang, EG Engleman - Drug Discovery Today: Disease Mechanisms, 2006 - Elsevier
Dendritic cells are specialized antigen-presenting cells that play a dual role in induction of
both innate and adaptive immunity as well as T cell tolerance. Dendritic cell based vaccines …

Does the immunocompetent status of cancer patients have an impact on therapeutic DC vaccination strategies?

S Martin Lluesma, M Graciotti, CLL Chiang… - Vaccines, 2018 - mdpi.com
Although different types of therapeutic vaccines against established cancerous lesions in
various indications have been developed since the 1990s, their clinical benefit is still very …

Dendritic cell based tumor vaccines

M Nouri-Shirazi, J Banchereau, J Fay, K Palucka - Immunology letters, 2000 - Elsevier
Dendritic cells (DC) constitute a unique system of cells that induce, sustain and regulate
immune responses. Distributed as sentinels throughout the body, DC are poised to capture …

Dendritic cell vaccination and other strategies to tip the balance of the immune system: DC2007 5th international meeting, July 16–18, Bamberg, Germany

N Schaft, K Birkholz, C Hofmann, M Schmid… - Cancer Immunology …, 2008 - Springer
The fifth international meeting on “Dendritic cell vaccination and other strategies to tip the
balance of the immune system” was held in Bamberg, Germany, on July 16–18, 2007. The 3 …

The evolving role of dendritic cells in cancer therapy

EJ Ilett, RJD Prestwich, AA Melcher - Expert Opinion on Biological …, 2010 - Taylor & Francis
Importance of the field: Dendritic cells (DC) are a clear choice for use in cancer
immunotherapy, and much research has focused on generating DC for clinical use …

Dendritic cell vaccine and cancer treatment: new patents

A AR Aleixo, MA Michelin… - Recent Patents on …, 2014 - ingentaconnect.com
Dendritic cell (DC) immunotherapy has been used to treat various types of tumors. Although
it is already in use in clinical practice, the mechanisms through which it acts need …

Dendritic cell-based vaccines: Shining the spotlight on signal 3

GP Linette, BM Carreno - Oncoimmunology, 2013 - Taylor & Francis
Dendritic cell (DC)-based anticancer vaccines have yielded disappointing results in a
multitude of clinical trials. New data suggest that the clinical efficacy of DC-based vaccines …

Dendritic cell-based cancer therapy.

C Conrad, FO Nestle - Current Opinion in Molecular Therapeutics, 2003 - europepmc.org
Dendritic cell (DC)-based cancer immunotherapy has been shown to be safe and feasible.
In clinical pilot studies, DCs primed with tumor antigens have successfully been used to …

Current state and perspectives of dendritic cell vaccination in cancer immunotherapy

A Farkas, C Conrad, G Tonel, Z Borbenyi… - Skin pharmacology and …, 2006 - karger.com
Recent progress in the approach towards immunotherapy of cancer consists in molecular
definition of tumor antigens, new tools for phenotypical and functional characterization of …

Antitumor vaccines based on dendritic cells: from experiments using animal tumor models to clinical trials

OV Markov, NL Mironova, VV Vlassov - Acta Naturae …, 2017 - cyberleninka.ru
The routine methods used to treat oncological diseases have a number of drawbacks,
including non-specific action and severe side effects for patients. Furthermore, tumor …