Obesity is associated with a distinct brain-gut microbiome signature that connects Prevotella and Bacteroides to the brain's reward center

TS Dong, M Guan, EA Mayer, J Stains, C Liu, P Vora… - Gut …, 2022 - Taylor & Francis
The prevalence of obesity has risen to its highest values over the last two decades. While
many studies have either shown brain or microbiome connections to obesity, few have …

A distinct brain‐gut‐microbiome profile exists for females with obesity and food addiction

TS Dong, EA Mayer, V Osadchiy, C Chang, W Katzka… - …, 2020 - Wiley Online Library
Background Alterations in brain‐gut‐microbiome interactions have been implicated as an
important factor in obesity. This study aimed to explore the relationship between food …

Gut microbiota interacts with brain microstructure and function

JM Fernandez-Real, M Serino, G Blasco… - The Journal of …, 2015 - academic.oup.com
Context: Evidence from animals suggests that gut microbiota affects brain structure and
function but evidence in humans is scarce. Objective: This study sought to evaluate potential …

[HTML][HTML] Gut microbiota phenotypes of obesity

MA Stanislawski, D Dabelea, LA Lange… - NPJ biofilms and …, 2019 - nature.com
Obesity is a disease with a complex etiology and variable prevalence across different
populations. While several studies have reported gut microbiota composition differences …

[HTML][HTML] The gut-brain axis, the human gut microbiota and their integration in the development of obesity

ES Bliss, E Whiteside - Frontiers in physiology, 2018 - frontiersin.org
Obesity is a global epidemic, placing socioeconomic strain on public healthcare systems,
especially within the so-called Western countries, such as Australia, United States, United …

Brain–gut–microbiome interactions in obesity and food addiction

A Gupta, V Osadchiy, EA Mayer - Nature Reviews Gastroenterology & …, 2020 - nature.com
Normal eating behaviour is coordinated by the tightly regulated balance between intestinal
and extra-intestinal homeostatic and hedonic mechanisms. By contrast, food addiction is a …

[HTML][HTML] The role of the gut microbiota in the gut–brain axis in obesity: mechanisms and future implications

J van Son, LL Koekkoek, SE La Fleur, MJ Serlie… - International Journal of …, 2021 - mdpi.com
Interaction between the gut and the brain is essential for energy homeostasis. In obesity, this
homeostasis is disrupted, leading to a positive energy balance and weight gain. Obesity is a …

[HTML][HTML] Interplay between the gut-brain axis, obesity and cognitive function

A Agustí, MP García-Pardo, I López-Almela… - Frontiers in …, 2018 - frontiersin.org
Obesity continues to be one of the major public health problems due to its high prevalence
and co-morbidities. Common co-morbidities not only include cardiometabolic disorders but …

Multimodal neuroimaging fusion biomarkers mediate the association between gut microbiota and cognition

J Zhu, C Wang, Y Qian, H Cai, S Zhang… - Progress in Neuro …, 2022 - Elsevier
Background The field of microbiota-gut-brain research in animals has progressed, while the
exact nature of gut microbiota-brain-cognition relationship in humans is not completely …

[HTML][HTML] Diet and exercise orthogonally alter the gut microbiome and reveal independent associations with anxiety and cognition

SS Kang, PR Jeraldo, A Kurti, MEB Miller… - Molecular …, 2014 - Springer
Background The ingestion of a high-fat diet (HFD) and the resulting obese state can exert a
multitude of stressors on the individual including anxiety and cognitive dysfunction. Though …