Nogo receptor-Fc delivered by haematopoietic cells enhances neurorepair in a multiple sclerosis model

S Ye, P Theotokis, JY Lee, MJ Kim, D Nheu… - Brain …, 2023 - academic.oup.com
Nogo receptor 1 is the high affinity receptor for the potent myelin-associated inhibitory
factors that make up part of the inflammatory extracellular milieu during experimental …

Nogo-A and nogo receptor expression in demyelinating lesions of multiple sclerosis

JI Satoh, H Onoue, K Arima… - … of Neuropathology & …, 2005 - academic.oup.com
A myelin-associated neurite outgrowth inhibitor, Nogo-A, plays a key role in inhibition of
axonal regeneration following injury and ischemia in the central nervous system (CNS) …

Lentiviral mediated expression of a NGF-soluble Nogo receptor 1 fusion protein promotes axonal regeneration

Y Zhang, F Gao, D Wu, P Moshayedi, X Zhang… - Neurobiology of …, 2013 - Elsevier
Abstract Nogo receptor 1 (NgR1) mediates the inhibitory effects of several myelin-associated
inhibitors (MAIs) on axonal regeneration in the central nervous system. A truncated soluble …

[HTML][HTML] Nogo receptor expression in microglia/macrophages during experimental autoimmune encephalomyelitis progression

AA Alrehaili, JY Lee, MM Bakhuraysah… - Neural regeneration …, 2018 - journals.lww.com
Myelin-associated inhibitory factors within the central nervous system (CNS) are considered
to be one of the main obstacles for axonal regeneration following disease or injury. The …

Myelin regulates immune cell adhesion and motility

M Pool, M Niino, I Rambaldi, K Robson, A Bar-Or… - Experimental …, 2009 - Elsevier
The etiology of multiple sclerosis (MS) has not been fully elucidated, however evidence
supports an autoimmune disease model notable for the infiltration of pro-inflammatory …

Nogo signaling and non‐physical injury‐induced nervous system pathology

FYH Teng, BL Tang - Journal of neuroscience research, 2005 - Wiley Online Library
The Nogo gene products were described first as myelin‐associated inhibitors that prevent
neuronal regeneration upon injury. Recent findings have also implicated Nogo in several …

[HTML][HTML] Soluble Nogo receptor down-regulates expression of neuronal Nogo-A to enhance axonal regeneration

X Peng, Z Zhou, J Hu, DJ Fink, M Mata - Journal of biological chemistry, 2010 - ASBMB
Nogo-A, a member of the reticulon family, is present in neurons and oligodendrocytes. Nogo-
A in central nervous system (CNS) myelin prevents axonal regeneration through interaction …

Targeting the Nogo receptor to treat central nervous system injuries

DHS Lee, SM Strittmatter, DWY Sah - Nature Reviews Drug Discovery, 2003 - nature.com
Axonal damage is a key pathology in many injuries of the central nervous system (CNS),
such as spinal cord injury, traumatic brain injury and stroke, as well as in multiple sclerosis …

Nogo and the Nogo-66 receptor

AE Fournier, T GrandPré, G Gould, X Wang… - Progress in brain …, 2002 - Elsevier
Nogo has been identified as a component of central nervous system (CNS) myelin
preventing axonal regeneration in the adult vertebrate CNS. Our previous analysis of Nogo …

The role of Nogo-A in neuroregeneration: a review

T Wang, JQ Xiong, XB Ren, W Sun - Brain Research Bulletin, 2012 - Elsevier
Nogo, also known as Reticulon-4, is a protein that is specific to the central nervous system
(CNS), and has been identified as an inhibitor of neurite outgrowth. Nogo-A is the largest …