Aurora B kinase is essential for faithful chromosome segregation during mitosis. During (pro)
metaphase, Aurora B is concentrated at the inner centromere by the kinases Haspin and …

Aurora B kinase plays an essential role in chromosome bi-orientation, which is a
prerequisite for equal segregation of chromosomes during mitosis. However, it remains …

Aurora B kinase has a critical role in regulating attachments between kinetochores and
spindle microtubules during mitosis. Early in mitosis, kinase activity at kinetochores is high to …

Error-free chromosome segregation is essential for the maintenance of genomic integrity
during cell division. Aurora B, the enzymatic subunit of the Chromosomal Passenger …

Haspin phosphorylates histone H3 at threonine-3 (H3T3ph), providing a docking site for the
Aurora B complex at centromeres. Aurora B functions to correct improper kinetochore …

Aurora B, a member of the Aurora family of serine/threonine protein kinases, is a key player
in chromosome segregation. As part of a macromolecular complex known as the …

Aurora B kinase regulates the proper biorientation of sister chromatids during mitosis. Lack
of Aurora B kinase function results in the inability to correct erroneous kinetochore …

The fidelity of chromosome segregation during mitosis is intimately linked to the function of
kinetochores, which are large protein complexes assembled at sites of centromeric …

By phosphorylating Thr3 of histone H3, Haspin promotes centromeric recruitment of the
chromosome passenger complex (CPC) during mitosis. Aurora B kinase, a CPC subunit …

Aurora B localization to mitotic centromeres, which is required for proper chromosome
alignment during mitosis, relies on Haspin‐dependent histone H3 phosphorylation and on …