2.1. Study design This prospective, multicenter, and observational study was conducted in
30 French pain clinics (Observational Ketamine And PaIn study Consortium). All included …

Background There is no recommendation in Europe for the use of ketamine in patients with
chronic pain. The heterogeneity of practice highlights the need to seek the advice of experts …

Objectives Ketamine is used to treat chronic refractory pain. However, there are no scientific
guidelines for ketamine use in the Netherlands. The aim of this survey was to provide an …

Ketamine is frequently used in the management of refractory chronic pain. To date, the level
of proof in the literature on ketamine in this type of indication is generally poor and …

Background This work summarizes the efficiency, failures and adverse effects of oral
administration of ketamine at home for intractable pain. Methods This 5‐year retrospective …

BACKGROUND: IV ketamine is widely used to treat patients with chronic pain, yet the long-
term impact remains uncertain. We synthesized evidence from randomized control trials to …

Ketamine is a dissociative anesthetic and its primary mechanism of action is considered to
be through antagonism of the N-methyl-D-aspartate (NMDA) receptor. For many years it has …

Ketamine has diverse effects that may be of relevance to chronic pain including: N-methyl-d-
aspartic acid, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid, kainate, γ …

Background Chronic pain significantly worsens the quality of life. Unlike neuropathic,
musculoskeletal, postoperative pain, and cancer pain, chronic primary pain cannot be …

Background Ketamine has been suggested to be efficient in relieving chronic pain.
However, there is inconsistency across studies investigating the effect of ketamine for …